Esculentoside B

Modify Date: 2024-01-03 00:19:20

Esculentoside B structure	Common Name	Esculentoside B
	CAS Number	60820-94-2	Molecular Weight	664.82
	Density	1.3±0.1 g/cm3	Boiling Point	779.3±60.0 °C at 760 mmHg
	Molecular Formula	C₃₆H₅₆O₁₁	Melting Point	N/A
	MSDS	N/A	Flash Point	237.0±26.4 °C

Use of Esculentoside B

Esculentoside B (Phytolaccoside B) is a natural product from the roots of Phytolacca acinosa Roxb. Esculentoside B is neurotoxic to zebrafish larvae, and impairs their central nervous system development. Esculentoside B inhibits inflammatory response and has antifungal activity[1][2][3].

Name	Phytolaccoside B
Synonym	More Synonyms

Description	Esculentoside B (Phytolaccoside B) is a natural product from the roots of Phytolacca acinosa Roxb. Esculentoside B is neurotoxic to zebrafish larvae, and impairs their central nervous system development. Esculentoside B inhibits inflammatory response and has antifungal activity[1][2][3].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal Research Areas >> Inflammation/Immunology Research Areas >> Neurological Disease Signaling Pathways >> MAPK/ERK Pathway >> JNK Signaling Pathways >> Neuronal Signaling >> AChE
References	[1]. Abekura F, et al. Esculentoside B inhibits inflammatory response through JNK and downstream NF-κB signaling pathway in LPS-triggered murine macrophage RAW 264.7 cells. Int Immunopharmacol. 2019;68:156-163. [2]. Ren S, et al. Metabolic exploration of the developmental abnormalities and neurotoxicity of Esculentoside B, the main toxic factor in Phytolaccae radix. Food Chem Toxicol. 2023;176:113777. [3]. Escalante A, et al. Evidence for the mechanism of action of the antifungal phytolaccoside B isolated from Phytolacca tetramera Hauman. J Nat Prod. 2008;71(10):1720-1725.

Description

Related Catalog

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Fungal

Research Areas >> Inflammation/Immunology

Research Areas >> Neurological Disease

Signaling Pathways >> MAPK/ERK Pathway >> JNK

Signaling Pathways >> Neuronal Signaling >> AChE

References

[1]. Abekura F, et al. Esculentoside B inhibits inflammatory response through JNK and downstream NF-κB signaling pathway in LPS-triggered murine macrophage RAW 264.7 cells. Int Immunopharmacol. 2019;68:156-163.

[2]. Ren S, et al. Metabolic exploration of the developmental abnormalities and neurotoxicity of Esculentoside B, the main toxic factor in Phytolaccae radix. Food Chem Toxicol. 2023;176:113777.

[3]. Escalante A, et al. Evidence for the mechanism of action of the antifungal phytolaccoside B isolated from Phytolacca tetramera Hauman. J Nat Prod. 2008;71(10):1720-1725.

Density	1.3±0.1 g/cm3
Boiling Point	779.3±60.0 °C at 760 mmHg
Molecular Formula	C₃₆H₅₆O₁₁
Molecular Weight	664.82
Flash Point	237.0±26.4 °C
Exact Mass	664.382263
PSA	183.21000
LogP	5.47
Vapour Pressure	0.0±6.1 mmHg at 25°C
Index of Refraction	1.600