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41060-16-6

41060-16-6 structure
41060-16-6 structure
  • Name: Panicolin
  • Chemical Name: Skullcapflavone I
  • CAS Number: 41060-16-6
  • Molecular Formula: C17H14O6
  • Molecular Weight: 314.29
  • Catalog: Natural product Flavonoids
  • Create Date: 2016-04-15 11:37:00
  • Modify Date: 2024-01-13 18:38:06
  • Skullcapflavone I can be isolated from A. nallamalayana. Skullcapflavone I inhibits collagenase and elastase enzyme with IC50s of 106.74 μM and 186.70 μM. Skullcapflavone I has anticancer activities by down-regulating miR-23a[1].

Name Skullcapflavone I
Synonyms SKULLCAPFLAVONE I
5-Hydroxy-2-(2-hydroxyphenyl)-7,8-dimethoxy-4H-chromen-4-one
4H-1-Benzopyran-4-one, 5-hydroxy-2-(2-hydroxyphenyl)-7,8-dimethoxy-
Panicolin
Description Skullcapflavone I can be isolated from A. nallamalayana. Skullcapflavone I inhibits collagenase and elastase enzyme with IC50s of 106.74 μM and 186.70 μM. Skullcapflavone I has anticancer activities by down-regulating miR-23a[1].
Related Catalog
References

[1]. Yang B, et al. Anti-cancer, Anti-collagenase and Anti-elastase Potentials of Some Natural Derivatives: In vitro and in silico Studies. J Oleo Sci. 2023;72(5):557-570.  

[2]. Cui J, et al. Skullcapflavone I has a potent anti-pancreatic cancer activity by targeting miR-23a. Biofactors. 2020 Sep;46(5):821-830.  

Density 1.4±0.1 g/cm3
Boiling Point 573.6±50.0 °C at 760 mmHg
Melting Point 254-256℃
Molecular Formula C17H14O6
Molecular Weight 314.29
Flash Point 215.5±23.6 °C
Exact Mass 314.079041
PSA 89.13000
LogP 2.06
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.646
Hazard Codes T+
HS Code 2914509090
HS Code 2914509090
Summary HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%