Resistance to filariasis and anti-leishmaniasis

Filariasis is an infectious disease caused by silkworm parasites in the human lymphatic system. The main drugs used for anti-filariasis are ethamazine, furose, and suramin sodium. The piperazine derivative, ethamazine, kills microfilariae from Malay, Ban, Timor, Roa and Onchocerca. Ethamazine is the drug of choice for the treatment of lymphatic filariasis since 1947. It can also be used to treat onchocerciasis and filariasis. Leishmaniasis is still mainly found in tropical and subtropical regions, where blood-sucking insects that transmit the disease live in these areas. The infection is caused by the presence of the amastigote of the Leishmania in the reticuloendothelial cells. The eastern hemisphere is the genus, the western hemisphere is the genus, and the storage host is the rodent and other small animals. Human organs, skin and mucous membranes or skin infections, from mild to self-limiting to severely different. Visceral leishmaniasis, a kala-azar caused by Leishmania donovani, is a potentially lethal infection in immunodeficient patients. In the case of normal immune function, it may linger in the host for many years, and only when the host causes the immune system to be inhibited for any reason. However, many patients have visceral leishmaniasis without significant immunosuppression. Visceral leishmaniasis usually begins with mild symptoms such as fever, weight loss, hepatosplenomegaly and liver dysfunction, hypoproteinemia, hypergammaglobulinemia, whole blood cell reduction, hemorrhage, and lymphadenopathy. Some patients in the affected area have no symptoms or mild symptoms. Although they have not been treated, the infection has not developed. On the other hand, the infection can also be fatal, especially for immunodeficiency. Malnutrition is also a significant risk factor for the development of visceral leishmaniasis. South American skin and mucosal leishmaniasis, mainly caused by Leishmania parasites, should be treated because of the development of mucosal ulcers in the mouth, sputum, pharynx and nose, often resulting in significant facial changes. Dermal leishmaniasis (eastern sore) is caused by tropical or large Leishmania (eastern leishmaniasis) and Brazilian, Mexican or Peruvian Leishmania (Western hemisphere leishmaniasis), but north to Texas The state can also see that there is a small nodule at the insect bite, and it will heal very slowly after crusting or rupture. Leishmania can often be found by taking tissue samples or culturing from the edge of a skin ulcer.