Name | megestrol acetate |
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Synonyms |
(8R,9S,10R,13S,14S,17R)-17-Acetyl-6,10,13-trimethyl-3-oxo-2,3,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-ylacetat
Megestil Pregna-4,6-diene-3,20-dione, 17-hydroxy-6-methyl-, acetate Megestin Pruritex Chat Felipil Nuvacon 6-Dehydro-6-methyl-17a-acetoxyprogesterone Citestrol Megace Pregna-4,6-diene-3,20-dione, 17-(acetyloxy)-6-methyl-, (9β,10α)- Megoestrolacetat Megostat 6-Methyl-3,20-dioxopregna-4,6-dien-17-yl acetate Megestrol acetate Megestrol acetate [USAN] 17α-Acetoxy-6-methylpregna-4,6-diene-3,20-dione Megestrol 17-acetate Pill'Kan Estropill Kombiquens Megefren EINECS 209-864-5 17α-Acetoxy-6-methyl-4,6-pregnadiene-3,20-dione Maygace Volidan 6-Methyl-D4,6-pregnadien-17a-ol-3,20-dione Acetate Pregna-4,6-diene-3,20-dione, 17-(acetyloxy)-6-methyl- 17a-Acetoxy-6-methylpregna-4,6-diene-3,20-dione Minigest Megestryl acetate Nia acétate de (8R,9S,10R,13S,14S,17R)-17-acétyl-6,10,13-triméthyl-3-oxo-2,3,8,9,10,11,12,13,14,15,16,17-dodécahydro-1H-cyclopenta[a]phénanthrén-17-yle 6-Dehydro-6-methyl-17α-acetoxyprogesterone Opochaleurs Suppress [(8R,9S,10R,13S,14S,17R)-17-acetyl-6,10,13-trimethyl-3-oxo-2,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-17-yl] acetate Megecat Volplan Progesterone, 6-dehydro-17-hydroxy-6-methyl-, acetate Pilucalm MFCD00056470 Gorda Canipil (8R,9S,10R,13S,14S,17R)-17-acetyl-6,10,13-trimethyl-3-oxo-2,3,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate Megestrol (Acetate) |
Description | Megestrol Acetate is a synthetic progesteronal agent with an IC50 of 260 μM for the inhibition of HegG2.Target: Progesterone ReceptorMegestrol acetate, also known as 17α-acetoxy-6-dehydro-6-methylprogesterone, and sometimes abbreviated as MGA or MA, is a steroidal progestin and progesterone derivative (specifically, a 17-hydroxylated progesterone) with predominantly progestational and antigonadotropic effects. Megestrol acetate is a good candidate for muscle wasting treatment and future studies addressed at the interaction between the drug and protein turnover in human skeletal muscle should be performed. |
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Related Catalog | |
References |
Density | 1.2±0.1 g/cm3 |
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Boiling Point | 507.1±50.0 °C at 760 mmHg |
Melting Point | 214°C |
Molecular Formula | C24H32O4 |
Molecular Weight | 384.509 |
Flash Point | 218.5±30.2 °C |
Exact Mass | 384.230072 |
PSA | 60.44000 |
LogP | 3.82 |
Vapour Pressure | 0.0±1.3 mmHg at 25°C |
Index of Refraction | 1.551 |
Storage condition | Refrigerator |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
MUTATION DATA
|
Symbol |
GHS08 |
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Signal Word | Warning |
Hazard Statements | H351-H373 |
Precautionary Statements | P281 |
Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
Hazard Codes | Xn:Harmful |
Risk Phrases | R40;R48 |
Safety Phrases | S22-S24/25 |
RIDADR | NONH for all modes of transport |
WGK Germany | 3 |
RTECS | TU4075000 |
Precursor 7 | |
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DownStream 1 | |