475-38-7

475-38-7 structure

Name: Naphthazarin
Chemical Name: naphthazarin
CAS Number: 475-38-7
Molecular Formula: C₁₀H₆O₄
Molecular Weight: 190.15200
Catalog: Chemical reagent Organic reagent Bicyclic compound
Create Date: 2018-08-27 11:32:51
Modify Date: 2024-01-03 16:30:31
Naphthazarin (DHNQ) is a naturally occurring compound. Naphthazarin is effective by various cellular mechanisms including oxidative stress, activation of mitochondrial apoptosis-inducing factor (AIF), depolymerization of microtubules, interference with lysosomal function and p53-dependent p21 activation. Naphthazarin triggers apoptosis and has anti-tumor effects[1][2].

Name	naphthazarin
Synonyms	5,8-Dihydroxy-1,4-naphthalenedione EINECS 207-495-4 MFCD00001685 5,8-Dihydroxy-1,4-naphthoquinone 5,8-dihydroxynaphthalene-1,4-dione Naphthazarin

Description	Naphthazarin (DHNQ) is a naturally occurring compound. Naphthazarin is effective by various cellular mechanisms including oxidative stress, activation of mitochondrial apoptosis-inducing factor (AIF), depolymerization of microtubules, interference with lysosomal function and p53-dependent p21 activation. Naphthazarin triggers apoptosis and has anti-tumor effects[1][2].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Research Areas >> Neurological Disease
References	[1]. Seon Young Choi, et al. Naphthazarin has a protective effect on the 1-methyl-4-phenyl-1,2,3,4-tetrahydropyridine-induced Parkinson's disease model. J Neurosci Res. 2012 Sep;90(9):1842-9. [2]. Omar Aljanadi, et al. Stimulation of Suicidal Erythrocyte Death by Naphthazarin. Basic Clin Pharmacol Toxicol. 2015 Dec;117(6):369-74.

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 124,25,1983

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi:Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S22-S24/25-S37/39-S26
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	QL7970000
HS Code	2914690090

HS Code	2914690090
Summary	2914690090 other quinones。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%