19249-03-7

19249-03-7 structure

Name: Triethylene glycol bis(p-toluenesulfonate)
Chemical Name: 2-[2-[2-(4-methylphenyl)sulfonyloxyethoxy]ethoxy]ethyl 4-methylbenzenesulfonate
CAS Number: 19249-03-7
Molecular Formula: C₂₀H₂₆O₈S₂
Molecular Weight: 458.546
Catalog: Chemical reagent Organic reagent Fatty alcohol
Create Date: 2018-08-28 22:39:06
Modify Date: 2024-01-02 13:39:20
Triethylene glycol bis(p-toluenesulfonate) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	2-[2-[2-(4-methylphenyl)sulfonyloxyethoxy]ethoxy]ethyl 4-methylbenzenesulfonate
Synonyms	Ethanol, 2,2'-(1,2-ethanediylbis(oxy))bis-, bis(4-methylbenzenesulfonate) 1,2-Ethanediylbis(oxy-2,1-ethanediyl) bis(4-methylbenzenesulfonate) 2-[2-(2-([(4-Methylphenyl)sulfonyl]oxy)ethoxy)ethoxy]ethyl 4-methylbenzenesulfonate TRI(ETHYLENE GLYCOL) DI-P-TOLUENESULFONATE ethane-1,2-diylbis(oxyethane-2,1-diyl) bis(4-methylbenzenesulfonate) Triethylene Glycol Bis(p-toluenesulfonate) TsOCH2(CH2OCH2)2CH2OTs Triethylene glycol di(p-toluenesulfonate) Triethylene Glycol Di-p-tosylate triethylene glycol bis(4-toluenesulfonate) 1,2-Bis(2-tosyloxyethoxy)ethane Ethanol, 2,2'-[1,2-ethanediylbis(oxy)]bis-, bis(4-methylbenzenesulfonate) bis-tosylated triethyleneglycol MFCD00048096 Triethylene glycol ditosylate 1,2-Bis[2-(p-toluenesulfonyloxy)ethoxy]ethane 2,2'-(Ethylenedioxy)diethyl Ditosylate (Ethane-1,2-diylbis(oxy))bis(ethane-2,1-diyl) bis(4-methylbenzenesulfonate) 2-(2-{2-[(4-methylphenyl)sulfonyloxy]ethoxy}ethoxy)ethyl 4-methylbenzenesulfon ate Tos-PEG4-Tos

Description	Triethylene glycol bis(p-toluenesulfonate) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. Snaebjornsson MT, et al. Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways. Exp Mol Med. 2018 Apr 16;50(4):34.

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi
Risk Phrases	R36/37/38
Safety Phrases	S26-S36
RIDADR	NONH for all modes of transport
WGK Germany	3
HS Code	2909309090

HS Code	2909309090
Summary	2909309090 other aromatic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%