32677-01-3

32677-01-3 structure

Name: H-Glu(OtBu)-OtBu.HCl
Chemical Name: ditert-butyl (2S)-2-aminopentanedioate,hydrochloride
CAS Number: 32677-01-3
Molecular Formula: C₁₃H₂₆ClNO₄
Molecular Weight: 295.803
Catalog: Biochemical Amino acids and their derivatives Glutamic acid derivative
Create Date: 2018-08-16 09:52:47
Modify Date: 2025-08-20 19:10:21
H-Glu(OtBu)-OtBu hydrochloride is a glutamate derivative that can be used for substance P antagonist synthesis[1].

Name	ditert-butyl (2S)-2-aminopentanedioate,hydrochloride
Synonyms	H-Glu(OtBu)-OtBu·HCl H-Glu(OtBu)-OtBuï¿½ï¿½HCl L-glutamic acid di-t-butyl ester hydrochloride MFCD00058003 Di-tert-butyl L-glutamate hydrochloride (1:1) L-Glutamic acid, bis(1,1-dimethylethyl) ester, hydrochloride (1:1) H-Glu(OtBu)-OtBu,HCl H-L-Glu(OtBu)-OtBu*HCl L-Glutamic acid di-tert L-Glutamic Acid di-Tert-Butyl Ester Hydrochloride Bis(2-methyl-2-propanyl) L-glutamate hydrochloride (1:1) (S)-Di-tert-butyl 2-aminopentanedioate hydrochloride H-Glu(OtBu)-OtBu.HCl L-Glutamic acid di-tert-butylester hydrochloride

Description	H-Glu(OtBu)-OtBu hydrochloride is a glutamate derivative that can be used for substance P antagonist synthesis[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> Neurokinin Receptor Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> Neurokinin Receptor
Target	Substance P[1]
References	[1]. Manolopoulou A, et al. Synthesis of potent antagonists of substance P by modifying the methionyl and glutaminyl residues of its C-terminal hexapeptide and without using D-amino acids. Int J Pept Protein Res. 1993 Apr;41(4):411-4.

CHEMICAL NAME :: L-Glutamic acid, bis(1,1-dimethylethyl)ester, hydrochloride

REFERENCE :: NTOTDY Neurobehavioral Toxicology and Teratology. (Fayetteville, NY) V.3-8, 1981-86. For publisher information, see NETEEC. Volume(issue)/page/year: 7,275,1985

REFERENCE :: NTOTDY Neurobehavioral Toxicology and Teratology. (Fayetteville, NY) V.3-8, 1981-86. For publisher information, see NETEEC. Volume(issue)/page/year: 7,275,1985

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	MA0880000

617-65-2

115-11-7

~84%

32677-01-3

Literature: US2004/87813 A1, ;

16881-41-7

32677-01-3

Literature: Recueil des Travaux Chimiques des Pays Bas, , vol. 102, # 11 p. 469 - 474

540-88-5

138-15-8

~40%

32677-01-3

Literature: Journal of Medicinal Chemistry, , vol. 37, # 20 p. 3294 - 3302