11029-61-1

11029-61-1 structure
11029-61-1 structure
  • Name: Gramicidin A
  • Chemical Name: gramicidin a
  • CAS Number: 11029-61-1
  • Molecular Formula: C99H140N20O17
  • Molecular Weight: 1882.29000
  • Catalog: API Synthetic anti-infective drugs Antifungal drugs
  • Create Date: 2018-02-09 08:00:00
  • Modify Date: 2026-06-30 17:46:53
  • Gramicidin A is a peptide component of gramicidin, an antibiotic mixture originally isolated from B. brevis. Gramicidin A is a highly hydrophobic channel-forming ionophore that forms channels in model membranes that are permeable to monovalent cations. Gramicidin A induces degradation of hypoxia inducible factor 1 α (HIF-1α).

Name gramicidin a
Synonyms amicidinafrombacillusbrevis
Alpha Foetoprotein,AFP
amicidin A, from Bacillus brevis, (HPLC)
AMICIDIN A
GLS2
gramicidinafrombacillusbrevis
imicidinA(HighPurity),Bacillusbrevis
OHC-NH-VAL-GLY-ALA-D-LEU-ALA-D-VAL-VAL-D-VAL-TRP-D-LEU-TRP-D-LEU-TRP-D-LEU-TRP-D-LEU-TRP-CONHCH2CH2OH
EINECS 234-259-8
hLGA
OHC-NH-VAL-GLY-ALA-D-LEU-ALA-D-VAL-VAL-D-VAL-TRP-D-LEU-TRP-D-LEU-TRP-D-LEU-TRP-CONCH2CH2OH
HCO-X-GLY-L-ALA-D-LEU-L-ALA-D-VAL-L-VAL-D-VAL-L-TRP-D-LEU-L-TRP-D-LEU-L-TRP-D-LEU-L-TRP-NHCH2CH2OH
HCO-VAL-GLY-ALA-D-LEU-ALA-D-VAL-VAL-D-VAL-TRP-D-LEU-TRP-D-LEU-TRP-D-LEU-NHCH2CH2OH
ANTI-GLS2 (C-TERM E513) antibody produced in rabbit
GrimicidinA(HighPurity),Bacillusbrevis
AMICIDIN A FROM BACILLUS BREVIS
α-fetoprotein,AFP
amicidin A, Antibiotic agent
AMICIDIN A, BACILLUS BREVIS
amicidin A, High Purity
Glutaminase liver isoform, mitochondrial
alpha 1 Fetoprotein Protein
AMICIDIN A //BP
IMICIDIN A
MFCD00466944
Alphafoetoprotein, Human
HCO-VAL-GLY-ALA-D-LEU-ALA-D-VAL-VAL-D-VAL-TRP-D-LEU-TRP-D-LEU-TRP-D-LEU-TRP-NHCH2CH2OH
amicidin A, High Purity, Bacillus brevis
GRIMICIDIN A
amicidin A, High Purity, Bacillus brevis - - Calbiochem
Description Gramicidin A is a peptide component of gramicidin, an antibiotic mixture originally isolated from B. brevis. Gramicidin A is a highly hydrophobic channel-forming ionophore that forms channels in model membranes that are permeable to monovalent cations. Gramicidin A induces degradation of hypoxia inducible factor 1 α (HIF-1α).
Related Catalog
Molecular Formula C99H140N20O17
Molecular Weight 1882.29000
Exact Mass 1881.07000
PSA 548.99000
LogP 11.26260
Appearance colorless or white
Storage condition 2-8°C
Water Solubility ethanol: soluble

CHEMICAL IDENTIFICATION

RTECS NUMBER :
MD8230000
CHEMICAL NAME :
Gramicidin A
CAS REGISTRY NUMBER :
11029-61-1
LAST UPDATED :
199309
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C148-H210-N30-O26
MOLECULAR WEIGHT :
2825.88

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 4(1),240,1980
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
60 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 4(1),240,1980
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
5 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 4(1),240,1980
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn: Harmful;
Risk Phrases 22
Safety Phrases 26-36
RIDADR NONH for all modes of transport
RTECS MD8230000
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