Top Suppliers:I want be here
Related CAS#:
524-55-0 5949-11-1
5949-12-2 24302-67-8
312695-48-0 146737-65-7
1406-14-0 6138-79-0
127228-87-9 1406-02-6
2271261-05-1 2224133-57-5
2003906-31-6 2224418-54-4
2224398-52-9 2224145-15-5
2185824-96-6 1695499-21-8
2353606-40-1 2229634-67-5

5949-11-1

5949-11-1 structure
5949-11-1 structure
  • Name: Cinchonine hydrochloride
  • Chemical Name: Cinchonine monohydrochloride hydrate
  • CAS Number: 5949-11-1
  • Molecular Formula: C19H23ClN2O
  • Molecular Weight: 330.852
  • Catalog: API Antiparasitic drug Antimalarial
  • Create Date: 2018-03-20 08:00:00
  • Modify Date: 2025-08-19 20:51:41
  • Cinchonine hydrochloride ((8R,9S)-Cinchonine hydrochloride) is a natural compound present in Cinchona bark. Cinchonine hydrochloride activates endoplasmic reticulum stress-induced apoptosis in human liver cancer cells[1].
Name Cinchonine monohydrochloride hydrate
Synonyms Cinchonan-9-ol, (9S)-, hydrochloride (1:1)
Cinchonan-9-ol, hydrochloride, (9S)-
Hydrogen chloride (9S)-cinchonan-9-ol (1:1:1)
cinchonan-9-ol,monohydrochloride, (9s)-
cinchonine hydrochloride hydrate
cinchonine hydrochloride dihydrate
cinchonine hydrochloride
cinchodinine dihydrochloride
cinchonine monohydrochloride dihydrate
cinchonine hydrochloride, hydrate
Cinchonan-9-ol, chloride, hydrogen salt, (9S)- (1:1)
l-cinchonine hydrochloride
Description Cinchonine hydrochloride ((8R,9S)-Cinchonine hydrochloride) is a natural compound present in Cinchona bark. Cinchonine hydrochloride activates endoplasmic reticulum stress-induced apoptosis in human liver cancer cells[1].
Related Catalog
References

[1]. Jin ZL, et al. Cinchonine activates endoplasmic reticulum stress-induced apoptosis in human liver cancer cells. Exp Ther Med. 2018 Jun;15(6):5046-5050.
Boiling Point 464.5ºC at 760 mmHg
Melting Point 208-218ºC(lit.)
Molecular Formula C19H23ClN2O
Molecular Weight 330.852
Exact Mass 330.149902
PSA 36.36000
LogP 3.90450

CHEMICAL IDENTIFICATION

RTECS NUMBER :
GD2962020
CHEMICAL NAME :
Cinchonan-9-ol, monohydrochloride, (9S)-
CAS REGISTRY NUMBER :
5949-11-1
LAST UPDATED :
199712
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C19-H22-N2-O.Cl-H
MOLECULAR WEIGHT :
330.89

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>150 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 52,2797,1992
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
720 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FRXXBL French Demande Patent Document. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #2550093
TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 52,2797,1992
Hazard Codes Xi,Xn
Risk Phrases R20/21/22
Safety Phrases 36/37-26
RIDADR UN 1544
WGK Germany 3
RTECS GD2962020
Packaging Group III
Hazard Class 6.1(b)
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Chemsrc provides CAS#:5949-11-1 MSDS, density, melting point, boiling point, structure, formula, molecular weight, synthetic route, etc.
title: CAS No. 5949-11-1 | Chemsrc address: https://m.chemsrc.com/en/baike/323279.html

Home | MSDS/SDS Database Search | Journals | Product Classification | Biologically Active Compounds | Selling Leads | About Us | Disclaimer

Copyright © 2024 ChemSrc All Rights Reserved