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17086-28-1

17086-28-1 structure

17086-28-1 structure

Name: Doxycycline
Chemical Name: doxycycline monohydrate
CAS Number: 17086-28-1
Molecular Formula: C₂₂H₂₆N₂O₉
Molecular Weight: 462.450
Catalog: API Antibiotics Other antibiotics
Create Date: 2018-08-30 19:33:19
Modify Date: 2026-07-07 19:32:55
Doxycycline monohydrate is an antibiotic and broad-spectrum metalloproteinase (MMP) inhibitor[1][2][3][4].

Name	doxycycline monohydrate
Synonyms	Doxytetracycline 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, (4S,4aR,5S,5aR,6R,12aS)-, hydrate (1:1) 6-Deoxy-5-oxytetracycline Monohydrate Doxycen 2-naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, (4S,4aR,5S,5aR,6R,12aS)-, monohydrate Doxycycline Monohydrate (4S,4,5S,5,6R,12aS)-4-(Dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-cboxamide hydrate DoxycyclineHyclate/Monohydrate24390-/Mono Power v1 Supracyclin a-6-Deoxy-S-hydroxytetracycline Monohydrate Doxycycline monohydrateQ: What is Doxycycline monohydrate Q: What is the CAS Number of Doxycycline monohydrate Q: What is the storage condition of Doxycycline monohydrate Q: What e the applications of Doxycycline monohydrate 5-Hydroxy-a-6-deoxytetracycline Monohydrate Doxycycline Hycate BP2000/Ph Eur 4/USP25 4-(Dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrote NSC-56228 Vibramycine (4S,4aR,5S,5aR,6R,12aS)-4-(Dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide hydrate (1:1) 4-(DIMETHYLAMINO)-1,4,4A,5,5A,6,11,12A-OCTAHYDRO-3,5,10,12,12A-PENTAHYDROXY-6-METHYL-1,11-DIOXO-2-NA Liviatin Spanor α-6-Deoxyoxytetracycline monohydrate (4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide hydrate Doxivetin Investin α-Doxycycline Doxy-Puren (4S,4aR,5S,5aR,6R,12aS)-4-(Dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydro-2-tetracenecarboxamide hydrate (1:1) (4S,4aR,5S,5aR,6R,12aS)-4-(diméthylamino)-3,5,10,12,12a-pentahydroxy-6-méthyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotétracène-2-carboxamide hydrate oxycyclinemonohydrate 5-Hydroxy-α-6-deoxytetracycline monohydrate NORDOX VIBRAVENOS 4-(DiMethylaMino)-3,5,10,12,12a-pentahydroxy-6-Methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxaMide hydrate DOXYCYCLINE MONOHYDRATE 4-(DIMETHYLAMINO)-1,4,4 ALPHA,5,5 ALPHA,6,11,12 ALPHA-OCTAHYDRO-3,5,10,12,12 ALPHA-PENTAHYDROXY-6-METHYL-1,11-DIOXO-2-NAPHTHACENECBOXAMIDE, MONOHYDRATE 2-Naphthacenecboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrate, (4S,4,5S,5,6R,12aS) 2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione hydrate Doxycycline Monohydrate/Doxycycline base [4S-(4a,4aa,5a,5aa,6a,12aa)]-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide Monohydrate (4S,4aR,5S,5aR,6R,12aS)-4-(Dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracen-2-carboxamidhydrat Doxitard a-6-Deoxyoxytetracycline Monohydrate Strong v1 Doxycycline monohydrate //BP Doxycycline Hycate BP2000/Ph Eur 4/25 a-Doxycycline DOXYCYCLINE HYDRATE Jenacyclin Doxycyeline HCL Deoxymykoin 4-(DiMethylaMino)-3,5,10,12,12a-pentahydroxy-6-Methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-cboxaMide hydrate

Description	Doxycycline monohydrate is an antibiotic and broad-spectrum metalloproteinase (MMP) inhibitor[1][2][3][4].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Metabolic Enzyme/Protease >> MMP
Target	MMP[1]
References	[1]. Wilfried Briest, et al. Doxycycline ameliorates the susceptibility to aortic lesions in a mouse model for the vascular type of Ehlers-Danlos syndrome. J Pharmacol Exp Ther. 2011 Jun;337(3):621-7. [2]. Zhang N, et al. The PK/PD Interactions of Doxycycline against Mycoplasma gallisepticum. Front Microbiol. 2016 May 4;7:653. [3]. Trajano VC, et al. Osteogenic activity of cyclodextrin-encapsulated doxycycline in a calcium phosphate PCL and PLGA composite. Mater Sci Eng C Mater Biol Appl. 2016 Jul 1;64:370-5. [4]. Morales R, et al. Inhibition of extracellular matrix production and remodeling by doxycycline in smooth muscle cells. J Pharmacol Sci. 2016 Mar 25. Epub ahead of print.

Boiling Point	819.4ºC at 760 mmHg
Melting Point	167-168℃
Molecular Formula	C₂₂H₂₆N₂O₉
Molecular Weight	462.450
Flash Point	449.4ºC
Exact Mass	462.163818
PSA	190.85000
LogP	0.28840
Vapour Pressure	2.07E-28mmHg at 25°C
Storage condition	-20°C
Water Solubility	DMSO: soluble1mg/mL \| Soluble in ethanol or methanol. Sparingly soluble in water.Soluble in dilute acids, alkali hydroxides and dimethyl sulfoxide.

Hazard Codes	Xi
Risk Phrases	R36/37/38
Safety Phrases	26-36/37
HS Code	29413000

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