Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Doxycycline monohydrate
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Purity: 98.0%
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DC Chemicals Limited
China
Product Name: Doxycycline monohydrate
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Purity: 98.0%
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 4-(DIMETHYLAMINO)-3,5,10,12,12A-PENTAHYDROXY-6-METHYL-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2-CARBOXAMIDE HYDRATE
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Purity: 98.0%
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Henan Tianfu Chemical Co., Ltd.
China
Product Name: Doxycycline Monohydrate
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson
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17086-28-1

17086-28-1 structure

17086-28-1 structure

Name: Doxycycline
Chemical Name: doxycycline monohydrate
CAS Number: 17086-28-1
Molecular Formula: C₂₂H₂₆N₂O₉
Molecular Weight: 462.450
Catalog: API Antibiotics Other antibiotics
Create Date: 2018-08-30 19:33:19
Modify Date: 2025-08-22 12:03:38
Doxycycline monohydrate is an antibiotic and broad-spectrum metalloproteinase (MMP) inhibitor[1][2][3][4].

Name	doxycycline monohydrate
Synonyms	Doxy-Puren Doxytetracycline (4S,4aR,5S,5aR,6R,12aS)-4-(Dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydro-2-tetracenecarboxamide hydrate (1:1) 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, (4S,4aR,5S,5aR,6R,12aS)-, hydrate (1:1) (4S,4aR,5S,5aR,6R,12aS)-4-(diméthylamino)-3,5,10,12,12a-pentahydroxy-6-méthyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotétracène-2-carboxamide hydrate 5-Hydroxy-α-6-deoxytetracycline monohydrate Doxycen NORDOX VIBRAVENOS 2-naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, (4S,4aR,5S,5aR,6R,12aS)-, monohydrate Doxycycline Monohydrate 4-(DiMethylaMino)-3,5,10,12,12a-pentahydroxy-6-Methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxaMide hydrate Supracyclin a-6-Deoxy-S-hydroxytetracycline Monohydrate 5-Hydroxy-a-6-deoxytetracycline Monohydrate Doxycycline Monohydrate/Doxycycline base [4S-(4a,4aa,5a,5aa,6a,12aa)]-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide Monohydrate Doxycycline Hycate BP2000/Ph Eur 4/USP25 (4S,4aR,5S,5aR,6R,12aS)-4-(Dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracen-2-carboxamidhydrat Doxitard a-6-Deoxyoxytetracycline Monohydrate Vibramycine a-Doxycycline DOXYCYCLINE HYDRATE Jenacyclin (4S,4aR,5S,5aR,6R,12aS)-4-(Dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide hydrate (1:1) 4-(DIMETHYLAMINO)-1,4,4A,5,5A,6,11,12A-OCTAHYDRO-3,5,10,12,12A-PENTAHYDROXY-6-METHYL-1,11-DIOXO-2-NA Liviatin Doxycycline Spanor α-6-Deoxyoxytetracycline monohydrate (4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide hydrate Doxivetin Deoxymykoin Investin α-Doxycycline

Description	Doxycycline monohydrate is an antibiotic and broad-spectrum metalloproteinase (MMP) inhibitor[1][2][3][4].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Metabolic Enzyme/Protease >> MMP
Target	MMP[1]
References	[1]. Wilfried Briest, et al. Doxycycline ameliorates the susceptibility to aortic lesions in a mouse model for the vascular type of Ehlers-Danlos syndrome. J Pharmacol Exp Ther. 2011 Jun;337(3):621-7. [2]. Zhang N, et al. The PK/PD Interactions of Doxycycline against Mycoplasma gallisepticum. Front Microbiol. 2016 May 4;7:653. [3]. Trajano VC, et al. Osteogenic activity of cyclodextrin-encapsulated doxycycline in a calcium phosphate PCL and PLGA composite. Mater Sci Eng C Mater Biol Appl. 2016 Jul 1;64:370-5. [4]. Morales R, et al. Inhibition of extracellular matrix production and remodeling by doxycycline in smooth muscle cells. J Pharmacol Sci. 2016 Mar 25. Epub ahead of print.

Boiling Point	819.4ºC at 760 mmHg
Melting Point	167-168℃
Molecular Formula	C₂₂H₂₆N₂O₉
Molecular Weight	462.450
Flash Point	449.4ºC
Exact Mass	462.163818
PSA	190.85000
LogP	0.28840
Vapour Pressure	2.07E-28mmHg at 25°C
Storage condition	-20°C
Water Solubility	DMSO: soluble1mg/mL \| Soluble in ethanol or methanol. Sparingly soluble in water.Soluble in dilute acids, alkali hydroxides and dimethyl sulfoxide.

Hazard Codes	Xi
Risk Phrases	R36/37/38
Safety Phrases	26-36/37
HS Code	29413000

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