Doxycycline

Modify Date: 2024-01-02 22:13:00

Doxycycline structure	Common Name	Doxycycline
	CAS Number	17086-28-1	Molecular Weight	462.450
	Density	N/A	Boiling Point	819.4ºC at 760 mmHg
	Molecular Formula	C₂₂H₂₆N₂O₉	Melting Point	167-168℃
	MSDS	N/A	Flash Point	449.4ºC

Use of Doxycycline

Doxycycline monohydrate is an antibiotic and broad-spectrum metalloproteinase (MMP) inhibitor[1][2][3][4].

Name	doxycycline monohydrate
Synonym	More Synonyms

Description	Doxycycline monohydrate is an antibiotic and broad-spectrum metalloproteinase (MMP) inhibitor[1][2][3][4].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Metabolic Enzyme/Protease >> MMP
Target	MMP[1]
References	[1]. Wilfried Briest, et al. Doxycycline ameliorates the susceptibility to aortic lesions in a mouse model for the vascular type of Ehlers-Danlos syndrome. J Pharmacol Exp Ther. 2011 Jun;337(3):621-7. [2]. Zhang N, et al. The PK/PD Interactions of Doxycycline against Mycoplasma gallisepticum. Front Microbiol. 2016 May 4;7:653. [3]. Trajano VC, et al. Osteogenic activity of cyclodextrin-encapsulated doxycycline in a calcium phosphate PCL and PLGA composite. Mater Sci Eng C Mater Biol Appl. 2016 Jul 1;64:370-5. [4]. Morales R, et al. Inhibition of extracellular matrix production and remodeling by doxycycline in smooth muscle cells. J Pharmacol Sci. 2016 Mar 25. Epub ahead of print.

Boiling Point	819.4ºC at 760 mmHg
Melting Point	167-168℃
Molecular Formula	C₂₂H₂₆N₂O₉
Molecular Weight	462.450
Flash Point	449.4ºC
Exact Mass	462.163818
PSA	190.85000
LogP	0.28840
Vapour Pressure	2.07E-28mmHg at 25°C
Storage condition	-20°C
Water Solubility	DMSO: soluble1mg/mL \| Soluble in ethanol or methanol. Sparingly soluble in water.Soluble in dilute acids, alkali hydroxides and dimethyl sulfoxide.

Doxycycline MSDS(Chinese)

Hazard Codes	Xi
Risk Phrases	R36/37/38
Safety Phrases	26-36/37
HS Code	29413000

Doxy-Puren

Doxytetracycline

(4S,4aR,5S,5aR,6R,12aS)-4-(Dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydro-2-tetracenecarboxamide hydrate (1:1)

2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, (4S,4aR,5S,5aR,6R,12aS)-, hydrate (1:1)

(4S,4aR,5S,5aR,6R,12aS)-4-(diméthylamino)-3,5,10,12,12a-pentahydroxy-6-méthyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotétracène-2-carboxamide hydrate

5-Hydroxy-α-6-deoxytetracycline monohydrate

Doxycen

NORDOX

VIBRAVENOS

2-naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, (4S,4aR,5S,5aR,6R,12aS)-, monohydrate

Doxycycline Monohydrate

4-(DiMethylaMino)-3,5,10,12,12a-pentahydroxy-6-Methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxaMide hydrate

Supracyclin

a-6-Deoxy-S-hydroxytetracycline Monohydrate

5-Hydroxy-a-6-deoxytetracycline Monohydrate

Doxycycline Monohydrate/Doxycycline base

[4S-(4a,4aa,5a,5aa,6a,12aa)]-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide Monohydrate

Doxycycline Hycate BP2000/Ph Eur 4/USP25

(4S,4aR,5S,5aR,6R,12aS)-4-(Dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracen-2-carboxamidhydrat

Doxitard

a-6-Deoxyoxytetracycline Monohydrate

Vibramycine

a-Doxycycline

DOXYCYCLINE HYDRATE

Jenacyclin

(4S,4aR,5S,5aR,6R,12aS)-4-(Dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide hydrate (1:1)

4-(DIMETHYLAMINO)-1,4,4A,5,5A,6,11,12A-OCTAHYDRO-3,5,10,12,12A-PENTAHYDROXY-6-METHYL-1,11-DIOXO-2-NA

Liviatin

Doxycycline

Spanor

α-6-Deoxyoxytetracycline monohydrate

(4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide hydrate

Doxivetin

Deoxymykoin

Investin

α-Doxycycline