102115-79-7
102115-79-7 structure
- Name: Pseudoprotodioscin
- Chemical Name: protogracellin
- CAS Number: 102115-79-7
- Molecular Formula: C51H82O21
- Molecular Weight: 1031.184
- Catalog: Biochemical Chinese herbal medicine ingredients
- Create Date: 2018-02-16 08:00:00
- Modify Date: 2026-07-08 17:38:51
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Pseudoprotodioscin, a furostanoside, inhibits SREBP1/2 and microRNA 33a/b levels and reduces the gene expression regarding the synthesis of cholesterol and triglycerides[1].
| Name | protogracellin |
|---|---|
| Synonyms |
Pseudoprotodioscin, 10 mM in DMSO
β-D-Glucopyranoside, (25R)-3-[[O-6-deoxy-α-L-mannopyranosyl-(1->2)-O-[6-deoxy-α-L-mannopyranosyl-(1->4)]-β-D-glucopyranosyl]oxy]furosta-5,20(22)-dien-27-yl (3β,25R)-26-(β-D-Glucopyranosyloxy)furosta-5,20(22)-dien-3-yl 6-deoxy-α-L-mannopyranosyl-(1->;2)-[6-deoxy-α-L-mannopyranosyl-(1->;4)]-β-D-glucopyranoside PROTODIOSCIN,PSEUDO (25R)-26-(β-D-Glucopyranosyloxy)furosta-5,20(22)-dien-3-yl 6-deoxy-α-L-mannopyranosyl-(1->2)-[6-deoxy-α-L-mannopyranosyl-(1->4)]-β-D-glucopyranoside PROTOACELLIN //BP PSEUDOPROTOTRIBESTIN pseudo-Protodioscin Pseudoprotodioscin(P) PROTODIOSCIN, PSEUDO PROTOACELLIN PSEUDO-PROTODIOSCIN Pseduoprotodioscin Protoacellin from Dioscorea opposita Thunb (2S,2'S,3R,3'R,4R,4'R,5R,5'R,6S,6'S)-6,6'-(((2R,3S,4S,5R,6R)-4-Hydroxy-2-(hydroxymethyl)-6-(((6,6bS,8aS,8bS,11aS,12aS,12bS)-6a,8a,9-trimethyl-10-((R)-3-methyl-4-(((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)butyl)-3,4,5,6,6a,6b,7,8,8a,8b,11a,12,12a,12b-tetradecahydro-1H-naphtho[2',1':4,5]indeno[2,1-b]furan-4-yl)oxy)tetrahydro-2H-pyran-3,5-diyl)bis(oxy))bis(2-methyltetrahydro-2H-pyran-3,4,5-triol) (25R)-3-{[6-Deoxy-α-L-mannopyranosyl-(1->2)-[6-deoxy-α-L-mannopyranosyl-(1->4)]-β-D-glucopyranosyl]oxy}furosta-5,20(22)-dien-27-yl β-D-glucopyranoside β-D-Glucopyranoside, (3β,25R)-26-(β-D-glucopyranosyloxy)furosta-5,20-dien-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[6-deoxy-α-L-mannopyranosyl-(1→4)] |
| Description | Pseudoprotodioscin, a furostanoside, inhibits SREBP1/2 and microRNA 33a/b levels and reduces the gene expression regarding the synthesis of cholesterol and triglycerides[1]. |
|---|---|
| Related Catalog | |
| In Vitro | In Hep G2 cells, Pseudoprotodioscin increases ABCA1 protein and mRNA levels, and promotes the effluxion of ApoA-1-mediated cholesterol. Pseudoprotodioscin inhibits SREBP1c and SREBP2 transcription by decreasing microRNA 33a/b levels. This procedure reciprocally lead to the increase of ABCA1 levels. In THP-1 macrophages, Pseudoprotodioscin shows the similar effect, which reduces HMGCR, FAS and ACC mRNA levels and promotes low density lipoprotein receptor by decreasing the PCSK9 levels[1]. |
| References |
| Density | 1.45 g/cm3 |
|---|---|
| Molecular Formula | C51H82O21 |
| Molecular Weight | 1031.184 |
| Exact Mass | 1030.534912 |
| PSA | 325.83000 |
| LogP | 5.31 |
| Index of Refraction | 1.631 |
| Safety Phrases | S24/25 |
|---|---|
| HS Code | 29389090 |