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950-99-2

950-99-2 structure
950-99-2 structure
  • Name: 2H-1-Benzopyran-6-ol,3,4-dihydro-2,2,5,7,8-pentamethyl
  • Chemical Name: 2,2,5,7,8-pentamethyl-3,4-dihydrochromen-6-ol
  • CAS Number: 950-99-2
  • Molecular Formula: C14H20O2
  • Molecular Weight: 220.30700
  • Catalog: Research Areas Cancer
  • Create Date: 2018-12-20 17:05:53
  • Modify Date: 2026-09-21 09:26:04
  • 2,2,5,7,8-Pentamethyl-6-Chromanol (PMC) is the anti-oxidant moiety of vitamin E (α-tocopherol). 2,2,5,7,8-Pentamethyl-6-Chromanol has potent androgen receptor (AR) signaling modulation and anti-cancer activity against prostate cancer cell lines[1].

Name 2,2,5,7,8-pentamethyl-3,4-dihydrochromen-6-ol
Synonyms 2,2,5,7,8-Pentamethyl-6-Chromanol, 10 mM in DMSO
Chromane C-1
MFCD00210347
APC-100
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,2,5,7,8-pentamethyl
6-Hydroxy-2,2,5,7,8-pentamethylchroman
PENTAMETHYL-6-HYDROXYCHROMAN, 2,2,5,7,8
2,2,5,7,8-pentamethylchroman-6-ol
inhibit,2,2,5,7,8 Pentamethyl 6 Chromanol,Androgen Rector,Inhibitor,2,2,5,7,8Pentamethyl6Chromanol
2,2,5,7,8-PENTAMETHYL-6-HYDROXYCHROMAN
2,2,5,7,8-Pentamethyl-1-hydroxychroman
2,2,5,7,8-pentamethyl-1-hydroxychroman
3,4-dihydro-2,2,5,7,8-pentamethyl-2H-1-Benzopyran-6-ol
2,2,5,7,8-PENTAMETHYL-6-CHROMANOL
2,2,5,7,8-Pentamethyl-6-chromanol
PMHCR
2,2,5,7,8-pentamethyl-6-hydroxy-chromane
Chromane C1
2,2,5,7,8-Pentamethyl-6-chromanolTMC-5
PROTOPANAXATRIOL(RG)
2,2,5,7,8-Pentamethyl-6-hydroxychroman
Chromanol C1
Chroman C1
Description 2,2,5,7,8-Pentamethyl-6-Chromanol (PMC) is the anti-oxidant moiety of vitamin E (α-tocopherol). 2,2,5,7,8-Pentamethyl-6-Chromanol has potent androgen receptor (AR) signaling modulation and anti-cancer activity against prostate cancer cell lines[1].
Related Catalog
References

[1]. Kyriakopoulos CE, et al. A multicenter phase 1/2a dose-escalation study of the antioxidant moiety of vitamin E 2,2,5,7,8-pentamethyl-6-chromanol (APC-100) in men with advanced prostate cancer. Invest New Drugs. 2016 Apr;34(2):225-30.

Density 1.034g/cm3
Boiling Point 344.3ºC at 760 mmHg
Melting Point 89-91ºC(lit.)
Molecular Formula C14H20O2
Molecular Weight 220.30700
Flash Point 146.1ºC
Exact Mass 220.14600
PSA 29.46000
LogP 3.42100
Index of Refraction 1.529
Hazard Codes Xi: Irritant;
Risk Phrases 36/37/38
Safety Phrases 26-36
HS Code 2932999099
HS Code 2932999099
Summary 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
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