Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Taraxeryl acetate
Price:
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang

BioBioPha
China
Product Name: Taraxeryl acetate
Price: ￥1250.0/5mg
Purity: 98.0%
Stocking Period: 10 Day
Contact: Xueping-Zheng

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Taraxeryl acetate
Price: ￥1920.0/5mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Taraxeryl acetate
Price: $280.0/20mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

2189-80-2

2189-80-2 structure

2189-80-2 structure

Name: Taraxeryl acetate
Chemical Name: taraxerol acetate
CAS Number: 2189-80-2
Molecular Formula: C₃₂H₅₂O₂
Molecular Weight: 468.754
Catalog: Natural product Moss
Create Date: 2018-06-01 08:00:00
Modify Date: 2024-01-01 22:32:44
Taraxerol acetate is a COX-1 and COX-2 inhibitor with IC50 values of 116.3 μM and 94.7 μM, respectively. Taraxerol acetate the has the anticancer potential and induces cell apoptosis[1].

Name	taraxerol acetate
Synonyms	Taraxerol monoacetate 3-Picenol, 1,2,3,4,4a,5,6,6a,8,8a,9,10,11,12,12a,12b,13,14,14a,14b-eicosahydro-4,4,6a,8a,11,11,12b,14b-octamethyl-, acetate, (3S,4aR,6aR,8aR,12aR,12bS,14aR,14bR)- Friedoolean-14-en-3-yl acetate D-Friedoolean-14-en-3beta-yl acetate Acetyl taraxerol Taraxerol Acetate Taraxenol acetate (3S,4aR,6aR,8aR,12aR,12bS,14aR,14bR)-4,4,6a,8a,11,11,12b,14b-Octamethyl-1,2,3,4,4a,5,6,6a,8,8a,9,10,11,12,12a,12b,13,14,14a,14b-icosahydro-3-picenyl acetate (3S,4aR,6aR,8aR,12aR,12bS,14aR,14bR)-4,4,6a,8a,11,11,12b,14b-Octamethyl-1,2,3,4,4a,5,6,6a,8,8a,9,10,11,12,12a,12b,13,14,14a,14b-icosahydropicen-3-yl acetate taraxeryl acetate

Description	Taraxerol acetate is a COX-1 and COX-2 inhibitor with IC50 values of 116.3 μM and 94.7 μM, respectively. Taraxerol acetate the has the anticancer potential and induces cell apoptosis[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> Immunology/Inflammation >> COX
Target	COX-1:116.3 μM (IC50) COX-2:94.7 μM (IC50)
In Vitro	Taraxerol acetate(10-150 µM; 24 or 48 hours) induces a dose- and time-dependent cytotoxic effects in the U87 cells, exhibits IC50 values of 34.2 and 28.4 µM, at 24 and 48 h, respectively[2]. Taraxerol acetate(10, 50 and 150 µM; 24 hours) induces cell apoptosis, the percentage of apoptotic cells increased from 7.3% in the control cells, to 16.1, 44.1 and in the 10, 50 and 150 µM taraxerol acetate-treated cells, respectively. Furthermore, taraxerol acetate treatment led to sub-G1 cell cycle arrest with a corresponding decrease in the number of S-phase cells[2].
References	[1]. Ubaid Ur Rehman1 A, et al. Molecular docking of taraxerol acetate as a new COX inhibitor. Journal of the Bangladesh Pharmacological Society [2]. Hong JF, et al. Anticancer activity of taraxerol acetate in human glioblastoma cells and a mouse xenograft model via induction of autophagy and apoptotic cell death, cell cycle arrest and inhibition of cell migration.Mol Med Rep. 2016 Jun;13(6):4541-8.

Density	1.0±0.1 g/cm3
Boiling Point	505.1±49.0 °C at 760 mmHg
Melting Point	303-305ºC
Molecular Formula	C₃₂H₅₂O₂
Molecular Weight	468.754
Flash Point	256.2±17.4 °C
Exact Mass	468.396729
PSA	26.30000
LogP	11.95
Vapour Pressure	0.0±1.3 mmHg at 25°C
Index of Refraction	1.529

Hazard Codes	Xi