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60-00-4

60-00-4 structure
60-00-4 structure
  • Name: Ethylenediaminetetraacetic acid
  • Chemical Name: Ethylenediaminetetraacetic acid
  • CAS Number: 60-00-4
  • Molecular Formula: C10H16N2O8
  • Molecular Weight: 292.243
  • Catalog: Organic raw materials Hydrocarbon compounds and their derivatives Hydrocarbon halide
  • Create Date: 2018-02-08 08:00:00
  • Modify Date: 2026-06-30 18:20:01
  • Ethylenediaminetetraacetic acid is the acid form of Edetate, a chelating agent with anti-hypercalcemic and anticoagulant properties. Ethylenediaminetetraacetic acid binds calcium and heavy metal ions, forming soluble stable complexes. Ethylenediaminetetraacetic acidis also used as an anticoagulant for blood specimens and is applied as a treatment of lead poisoning[1].
Name Ethylenediaminetetraacetic acid
Synonyms Ethylenediaminetetraacetate
EDTA, free base
cheeloxbfacid
chemcolox340
N,N’-1,2-ethanediylbis[N-(cboxymethyl)-Glycine
(Ethylenedintrilo)tetraacetic acid
acideethylenediaminetetracetique(french)
Celon ath
{[2-(Bis-cboxymethyl-amino)-ethyl]-cboxymethyl-amino}-acetic acid
2,2',2'',2'''-(ethane-1,2-diyldinitrilo)tetraacetic acid
Nullapon B acid
Metaquest A
Hampene
Nullapon bf acid
(ethylenedinitrilo)tetra-aceticaci
([2-(Bis-cboxymethyl-amino)-ethyl]-cboxymethyl-amino)-acetic acid
kyselinaethylendiamintetraoctova
n,n’-1,2-ethanediylbis
Edetic
Cheelox
komplexonii
Acetic acid, (ethylenedinitrilo)tetra
Celon A
Havidote
Acide ethylenediaminetetracetique
edta(chelatingagent)
acideethylenediaminetetracetique
icrf185
Cheelox bf acid
Complexon ii
ethylenediaminetetraaceticacid(edta)
n,n’-1,2-ethanediylbis[n-(cboxymethyl)-glycin
4-04-00-02449 (Beilstein Handbook Reference)
Versene acid
2,2’,2’’,2’’’-(1,2-ethanediyldinitrilo)tetrakis-aceticaci
Komplexon ii
nervanaidbacid
glumacleanser
celonath
Kalex acids
3,6-bis(cboxymethyl)-6-diazaoctanedioicacid
2,2',2'',2'''-(1,2-Ethanediyldinitrilo)tetraacetic acid
Ethylene diamine tetraacetic acid
ethylenediamine-N,N,N',N'-tetraacetic acid
3,6-Diazaoctanedioic acid, 3,6-bis(cboxymethyl)
complexonii
Kyselina ethylendiamintetraoctova
Ethylenediamine tetraacetic acid
N,N’-1,2-Ethanediylbis[N-(cboxymethyl)]glycine
caswellno438
apesticidechemicalcode039101
nullaponbfacid
Endrate
n,n’-1,2-ethanediylbis(n-(cboxymethyl)-glycin
celona
EINECS 200-449-4
nullaponbacid
EDTA
clewattaa
edetic acid
Nervanaid B acid
Diaminoethanetetra-acetic acid
metaquesta
Glycine, N,N'-1,2-ethanediylbis[N-(cboxymethyl)
n,n’-1,2-ethanediylbis(n-(cboxymethyl)glycine)
Chemcolox
N,N'-1,2-Ethanediylbis[N-(carboxymethyl)glycine]
EDTA, free acid
ai3-17181
MFCD00003541
Description Ethylenediaminetetraacetic acid is the acid form of Edetate, a chelating agent with anti-hypercalcemic and anticoagulant properties. Ethylenediaminetetraacetic acid binds calcium and heavy metal ions, forming soluble stable complexes. Ethylenediaminetetraacetic acidis also used as an anticoagulant for blood specimens and is applied as a treatment of lead poisoning[1].
Related Catalog
References

[1]. Robert S Chumanov, et al. Artifact-inducing enrichment of ethylenediaminetetraacetic acid and ethyleneglycoltetraacetic acid on anion exchange resins. Anal Biochem. 2011 May 1;412(1):34-9.
Density 1.6±0.1 g/cm3
Boiling Point 614.2±55.0 °C at 760 mmHg
Melting Point 250 °C (dec.)(lit.)
Molecular Formula C10H16N2O8
Molecular Weight 292.243
Flash Point 325.2±31.5 °C
Exact Mass 292.090668
PSA 155.68000
LogP -0.43
Vapour Pressure 0.0±3.8 mmHg at 25°C
Index of Refraction 1.580
Storage condition 2-8°C
Stability Stable. Incompatible with copper, copper alloys, nickel, aluminium, strong oxidizing agents, strong bases
Water Solubility 0.5 g/L (25 ºC)

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AH4025000
CHEMICAL NAME :
Acetic acid, (ethylenedinitrilo)tetra-
CAS REGISTRY NUMBER :
60-00-4
BEILSTEIN REFERENCE NO. :
1716295
LAST UPDATED :
199710
DATA ITEMS CITED :
24
MOLECULAR FORMULA :
C10-H16-N2-O8
MOLECULAR WEIGHT :
292.28
WISWESSER LINE NOTATION :
QV1N1VQ2N1VQ1VQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
397 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
30 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
28500 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
7632 mg/kg
SEX/DURATION :
female 7-14 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - eye/ear Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue) Reproductive - Specific Developmental Abnormalities - musculoskeletal system
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
7632 mg/kg
SEX/DURATION :
female 7-14 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - cardiovascular (circulatory) system Reproductive - Specific Developmental Abnormalities - respiratory system Reproductive - Specific Developmental Abnormalities - urogenital system
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
7632 mg/kg
SEX/DURATION :
female 7-14 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
3 gm/kg
SEX/DURATION :
female 7-14 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
TYPE OF TEST :
Micronucleus test
TYPE OF TEST :
Micronucleus test
TYPE OF TEST :
Cytogenetic analysis

MUTATION DATA

TYPE OF TEST :
DNA inhibition
TEST SYSTEM :
Rodent - rabbit Kidney
DOSE/DURATION :
250 umol/L
REFERENCE :
ECREAL Experimental Cell Research. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.10- 1950- Volume(issue)/page/year: 36,92,1964 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 80283 No. of Facilities: 12157 (estimated) No. of Industries: 122 No. of Occupations: 93 No. of Employees: 121906 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 80283 No. of Facilities: 14680 (estimated) No. of Industries: 119 No. of Occupations: 116 No. of Employees: 509055 (estimated) No. of Female Employees: 315637 (estimated)
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H319
Precautionary Statements P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant
Risk Phrases R36/37/38
Safety Phrases S26-S61-S37/39-S36
RIDADR UN 3077 9/PG 3
WGK Germany 2
RTECS AH4025000
HS Code 2921219000
HS Code 2922499990
Summary HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%
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