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China
Product Name: Methyl L-pyroglutamate
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Dayang Chem (Hangzhou) Co., Ltd.
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Product Name: Methyl L-pyroglutamate
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4931-66-2

4931-66-2 structure

4931-66-2 structure

Name: Methyl L-Pyroglutamate
Chemical Name: Methyl L-Pyroglutamate
CAS Number: 4931-66-2
Molecular Formula: C₆H₉NO₃
Molecular Weight: 143.141
Catalog: Biochemical Amino acids and their derivatives Glutamic acid derivative
Create Date: 2018-04-26 08:00:00
Modify Date: 2026-07-16 17:47:42
Methyl L-pyroglutamate ((S)-Methyl 5-oxopyrrolidine-2-carboxylate;L-Pyroglutamic acid methyl ester) is isolated from P. oleracea and has anti-inflammatory activity[1].

Name	Methyl L-Pyroglutamate
Synonyms	H-PYR-OME (S)-5-Oxo-2-pyrrolidinecboxylic acid methyl ester Methyl L-pyroglutamate, 10 mM in DMSO L-5-OXO-2-PYRROLIDINECBOXYLIC ACID METHYL ESTER Methyl (S)-5-Oxopyrrolidine-2-cboxylate (2S)-5-Oxopyrrolidine-2-cboxylic acid methyl ester (+)-L-PYROGLUTAMIC ACID METHYL ESTER L-Pyr-OMe-OH L-PYR-OME METHYL L-PYROGLUTAMATE Methyl (S)-2-pyrrolidone-6-cboxylate (S)-5-Oxopyrrolidine-2-cboxylic Acid Methyl Ester Methyl (S)-(+)-2-Pyrrolidone-5-carboxylate (S)-(+)-METHYL 2-PYRROLODINE-5-CBOXYLATE methyl (2S)-5-oxopyrrolidine-2-carboxylate MethylL-Pyroglutamate> 5-Oxo-L-proline methyl ester H-pyroGlu-OMe Methyl L-pyroglutamate //BP (S)-5-(Methoxycbonyl)-2-pyrrolidinone H-PGLU-OME (S)-(+)-METHYL 2-PYRROLIDONE-5-CBOXYLATE PYR-OME methyl 5-oxo-L-prolinate (S)-5-Oxoproline methyl ester methyl (2S)-5-oxopyrrolidine-2-cboxylate (S)-Methyl5-oxopyrrolidine-2-cboxylate pGlu-OMe (S)-5-Oxopyrrolidine-2-carboxylic Acid Methyl Ester MFCD00080931 Methyl PyroglutaMate L-Pyroglutamic acid methylester EINECS 225-567-3 Pyr-OMe-OH L-Pyroglutamic Acid Methyl Ester Methyl (S)-5-Oxopyrrolidine-2-cboxylate (S)-5-Oxopyrrolidine-2-cboxylic Acid Methyl Ester L-Proline, 5-oxo-, Methyl ester METHYL (S)-2-PYRROLIDINONE-5-CBOXYLATE (2S)-5-Oxopyrrolidine-2α-cboxylic acid methyl ester 2-PYRROLIDONE-5-CBOXYLIC ACID METHYL ESTER (2S)-1-Methyl-5-oxopyrrolidine-2-cboxylate Methyl 5-oxo-L-prolinate DL-Proline, 5-oxo-, methyl ester L-5-Oxoproline Methyl Ester Pyroglutamic acid methyl ester Methyl (S)-(+)-2-pyrrolidone-5-cboxylate Pyr-OMe/Pyr-Oet Methyl (S)-2-Oxopyrrolidine-5-cboxylate L-Pyroglutamic Acid Methyl Ester (S)-PYROGLUTAMIC ACID METHYL ESTER L-PYROGLUTAMIC ACID METHYL ESTER H-L-Pyr-OMe Methyl (S)-(+)-2-pyrrolidone-2-cboxylate Methyl (S)-(+)-2-pyrrolidone-5-cboxylate (HPLC, Chiral purity) Methyl L-Pyroglutamate,e.e Methyl (S)-5-Oxopyrrolidine-2-carboxylate L-Proline, 5-oxo-, methyl ester

Description	Methyl L-pyroglutamate ((S)-Methyl 5-oxopyrrolidine-2-carboxylate;L-Pyroglutamic acid methyl ester) is isolated from P. oleracea and has anti-inflammatory activity[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Kim KH, et al. 1-Carbomethoxy-β-Carboline, Derived from Portulaca oleracea L., Ameliorates LPS-Mediated Inflammatory Response Associated with MAPK Signaling and Nuclear Translocation of NF-κB.Molecules. 2019 Nov 7;24(22). pii: E4042.

Density	1.2±0.1 g/cm3
Boiling Point	304.7±35.0 °C at 760 mmHg
Molecular Formula	C₆H₉NO₃
Molecular Weight	143.141
Flash Point	138.1±25.9 °C
Exact Mass	143.058243
PSA	55.40000
LogP	-1.92
Vapour Pressure	0.0±0.6 mmHg at 25°C
Index of Refraction	1.465

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	Xi:Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S36
RIDADR	NONH for all modes of transport
HS Code	2933790090

Precursor 10
98-79-3 67-56-1 149-87-1 77-76-9
108963-94-6 7664-93-9 7757-82-6 75857-94-2
88668-76-2 108963-96-8
DownStream 10
106191-02-0 42435-88-1 364750-80-1 59936-29-7
145414-30-8 51693-17-5 64700-65-8 4931-66-2
4931-68-4 84285-34-7

HS Code	2933790090
Summary	2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0%

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