Methyl L-Pyroglutamate

Modify Date: 2025-08-26 13:36:17

Methyl L-Pyroglutamate Structure
Methyl L-Pyroglutamate structure
Common Name Methyl L-Pyroglutamate
CAS Number 4931-66-2 Molecular Weight 143.141
Density 1.2±0.1 g/cm3 Boiling Point 304.7±35.0 °C at 760 mmHg
Molecular Formula C6H9NO3 Melting Point N/A
MSDS USA Flash Point 138.1±25.9 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of Methyl L-Pyroglutamate


Methyl L-pyroglutamate ((S)-Methyl 5-oxopyrrolidine-2-carboxylate;L-Pyroglutamic acid methyl ester) is isolated from P. oleracea and has anti-inflammatory activity[1].

 Names

Name Methyl L-Pyroglutamate
Synonym More Synonyms

 Methyl L-Pyroglutamate Biological Activity

Description Methyl L-pyroglutamate ((S)-Methyl 5-oxopyrrolidine-2-carboxylate;L-Pyroglutamic acid methyl ester) is isolated from P. oleracea and has anti-inflammatory activity[1].
Related Catalog
References

[1]. Kim KH, et al. 1-Carbomethoxy-β-Carboline, Derived from Portulaca oleracea L., Ameliorates LPS-Mediated Inflammatory Response Associated with MAPK Signaling and Nuclear Translocation of NF-κB.Molecules. 2019 Nov 7;24(22). pii: E4042.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 304.7±35.0 °C at 760 mmHg
Molecular Formula C6H9NO3
Molecular Weight 143.141
Flash Point 138.1±25.9 °C
Exact Mass 143.058243
PSA 55.40000
LogP -1.92
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.465

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36
RIDADR NONH for all modes of transport
HS Code 2933790090

 Synthetic Route

 Customs

HS Code 2933790090
Summary 2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0%

 Synonyms

L-Pyroglutamic Acid Methyl Ester
DL-Proline, 5-oxo-, methyl ester
EINECS 225-567-3
Methyl (S)-(+)-2-Pyrrolidone-5-carboxylate
methyl (2S)-5-oxopyrrolidine-2-carboxylate
(S)-5-Oxopyrrolidine-2-carboxylic Acid Methyl Ester
MFCD00080931
Methyl (S)-5-Oxopyrrolidine-2-carboxylate
L-Proline, 5-oxo-, methyl ester
Methyl 5-oxo-L-prolinate
L-Pyroglutamic acid methylester
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