Name | FMOC-L-Aspartic acid β-tert-butyl ester |
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Synonyms |
L-Aspartic acid, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, 4-(1,1-dimethylethyl) ester
FMOC-L-Asparticacidbeta-tert-butylester 4-tert-Butyl hydrogen N-((9H-fluoren-9-ylmethoxy)carbonyl)-L-aspartate (2S)-2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-4-[(2-methyl-2-propanyl)oxy]-4-oxobutanoic acid MFCD00037131 FMOC-L-Aspartic acid beta-tert-butyl ester N-α-FMOC-L-aspartic acid β-tert-butyl ester Fmoc-L-aspartic acid 4-tert-butyl ester Fmoc-Asp(OtBu)-OH EINECS 276-251-7 (2S)-4-tert-Butoxy-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-4-oxobutanoic acid (non-preferred name) 9-fluorenyl-methoxycarbonyl-L-Asp-tert-butyl ester |
Description | Fmoc-Asp(OtBu)-OH (4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate) is a aspartate derivative containing amine protecting group Fmoc. Fmoc-Asp(OtBu)-OH can be used for peptide synthesis[1]. |
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Related Catalog | |
References |
Density | 1.3±0.1 g/cm3 |
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Boiling Point | 620.8±55.0 °C at 760 mmHg |
Melting Point | 148-150 °C (dec.) |
Molecular Formula | C23H25NO6 |
Molecular Weight | 411.448 |
Flash Point | 329.3±31.5 °C |
Exact Mass | 411.168182 |
PSA | 101.93000 |
LogP | 5.16 |
Vapour Pressure | 0.0±1.9 mmHg at 25°C |
Index of Refraction | 1.576 |
Storage condition | 2~8°C |
Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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Hazard Codes | Xi: Irritant; |
Risk Phrases | R36/37/38 |
Safety Phrases | S24/25 |
RIDADR | NONH for all modes of transport |
WGK Germany | 3 |
HS Code | 2924299090 |
~62% 71989-14-5 |
Literature: Nowshuddin, Shaik; Rao; Reddy, A. Ram Synthetic Communications, 2009 , vol. 39, # 11 p. 2022 - 2031 |
~78% 71989-14-5 |
Literature: Schoen, Istvan; Kisfaludy, Lajos Synthesis, 1986 , # 4 p. 303 - 305 |
~62% 71989-14-5 |
Literature: Henklein, Peter; Heyne, Hans-Ulrich; Halatsch, Wolf-Rainer; Niedrich, Hartmut Synthesis, 1987 , # 2 p. 166 - 167 |
~68% 71989-14-5 |
Literature: Echner, Hartmut; Voelter, Wolfgang Liebigs Annalen der Chemie, 1988 , p. 1095 - 1098 |
~% 71989-14-5 |
Literature: Journal of Organic Chemistry, , vol. 77, # 23 p. 10575 - 10582 |
~% 71989-14-5 |
Literature: Synthesis, , # 2 p. 166 - 167 |
~% 71989-14-5
Detail
|
Literature: Synthesis, , # 7 p. 571 - 572 |
~% 71989-14-5 |
Literature: Tetrahedron Letters, , vol. 34, # 2 p. 323 - 326 |
~% 71989-14-5 |
Literature: Synthesis, , # 2 p. 166 - 167 |
Precursor 8 | |
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DownStream 10 | |
HS Code | 2924299090 |
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Summary | 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |