21913-98-4

21913-98-4 structure

Name: 3'-Methoxydaidzein
Chemical Name: 7,4'-dihydroxy-3'-methoxyisoflavone
CAS Number: 21913-98-4
Molecular Formula: C₁₆H₁₂O₅
Molecular Weight: 284.26
Catalog: Natural product Flavonoids
Create Date: 2016-03-30 04:16:42
Modify Date: 2024-01-02 18:08:58
3'-Methoxydaidzein is a isoflavone and a Sodium Channel inhibitor. 3'-Methoxydaidzein inhibits subtypes NaV1.7, NaV1.8 and NaV1.3 with IC50 of 181 nM, 397 nM, and 505 nM, respectively. 3'-Methoxydaidzein exerts analgesic activity by inhibiting voltage-gated sodium channels[1].

Name	7,4'-dihydroxy-3'-methoxyisoflavone
Synonyms	Isoflavone,4',7-dihydroxy-3'-methoxy 3'-Methoxydaidzein 7-hydroxy-3-(4-hydroxy-3-methoxyphenyl)chromen-4-one 4H-1-Benzopyran-4-one, 7-hydroxy-3-(4-hydroxy-3-methoxyphenyl)- 4',7-dihydroxy-3'-methoxyisoflavone 7,4'-dihydroxy-3'-methoxy-isoflavone 7-Hydroxy-3-(4-hydroxy-3-methoxyphenyl)-4H-chromen-4-one

Description	3'-Methoxydaidzein is a isoflavone and a Sodium Channel inhibitor. 3'-Methoxydaidzein inhibits subtypes NaV1.7, NaV1.8 and NaV1.3 with IC50 of 181 nM, 397 nM, and 505 nM, respectively. 3'-Methoxydaidzein exerts analgesic activity by inhibiting voltage-gated sodium channels[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> Sodium Channel Research Areas >> Neurological Disease
Target	Nav1.3:505 nM (IC50) Nav1.7:181 nM (IC50) Nav1.8:397 nM (IC50)
References	[1]. Xu RJ, et al. 3'-Methoxydaidzein exerts analgesic activity by inhibiting voltage-gated sodium channels. Chin J Nat Med. 2019 Jun;17(6):413-423.

Hazard Codes	Xi
HS Code	2914509090

HS Code	2914509090
Summary	HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%