6920-38-3

6920-38-3 structure

Name: Luteolin-4'-O-glucoside
Chemical Name: luteolin-4'-o-glucoside
CAS Number: 6920-38-3
Molecular Formula: C₂₁H₂₀O₁₁
Molecular Weight: 448.37700
Catalog: Biochemical Plant extracts
Create Date: 2018-06-17 16:28:40
Modify Date: 2024-01-02 23:48:38
Luteolin-4'-O-glucoside is an IL-5 inhibitor with an IC50 of 3.7 μM. Luteolin-4'-O-glucoside resists hyperuricemia and acute gouty arthritis activity. Luteolin-4'-O-glucoside shows anticancer activity[1][2][3].

Name	luteolin-4'-o-glucoside
Synonyms	luteolin-4'-glucoside 3',4',5,7-tetrahydroxyflavone-4'-glucoside MFCD00017468

Description	Luteolin-4'-O-glucoside is an IL-5 inhibitor with an IC50 of 3.7 μM. Luteolin-4'-O-glucoside resists hyperuricemia and acute gouty arthritis activity. Luteolin-4'-O-glucoside shows anticancer activity[1][2][3].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Immunology/Inflammation >> Interleukin Related Research Areas >> Inflammation/Immunology
Target	IC50: 3.7 μM (IL-5)[1]
In Vitro	Luteolin-4'-O-glucoside shows cytotoxic activity against NCI-H929, U266, and OPM2 cell lines[3].
References	[1]. Park KY, et al. Inhibitory effect of luteolin 4'-O-glucoside from Kummerowia striata and other flavonoids on interleukin-5 bioactivity. Planta Med. 1999 Jun;65(5):457-9. [2]. Lin Y, et al. Luteolin-4'-O-glucoside and its aglycone, two major flavones of Gnaphalium affine D. Don, resist hyperuricemia and acute gouty arthritis activity in animal models. Phytomedicine. 2018 Mar 1;41:54-61. [3]. Xu T, et al. Glycosylation of luteolin in hydrophilic organic solvents and structure–antioxidant relationships of luteolin glycosides. RSC Advances, 2022, 12(28): 18232-18237.

Hazard Codes	Xi

133-89-1

491-70-3

6920-38-3

70404-47-6

6920-38-3

5373-11-5