Luteolin-4'-O-glucoside

Modify Date: 2026-07-01 15:27:11

Luteolin-4'-O-glucoside structure	Common Name	Luteolin-4'-O-glucoside
	CAS Number	6920-38-3	Molecular Weight	448.37700
	Density	1.713g/cm3	Boiling Point	814.5ºC at 760 mmHg
	Molecular Formula	C₂₁H₂₀O₁₁	Melting Point	210ºC (dec.)
	MSDS	N/A	Flash Point	288.5ºC

Use of Luteolin-4'-O-glucoside

Luteolin-4'-O-glucoside is an IL-5 inhibitor with an IC50 of 3.7 μM. Luteolin-4'-O-glucoside resists hyperuricemia and acute gouty arthritis activity. Luteolin-4'-O-glucoside shows anticancer activity[1][2][3].

Name	luteolin-4'-o-glucoside
Synonym	More Synonyms

Description	Luteolin-4'-O-glucoside is an IL-5 inhibitor with an IC50 of 3.7 μM. Luteolin-4'-O-glucoside resists hyperuricemia and acute gouty arthritis activity. Luteolin-4'-O-glucoside shows anticancer activity[1][2][3].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Immunology/Inflammation >> Interleukin Related Research Areas >> Inflammation/Immunology
Target	IC50: 3.7 μM (IL-5)[1]
In Vitro	Luteolin-4'-O-glucoside shows cytotoxic activity against NCI-H929, U266, and OPM2 cell lines[3].
References	[1]. Park KY, et al. Inhibitory effect of luteolin 4'-O-glucoside from Kummerowia striata and other flavonoids on interleukin-5 bioactivity. Planta Med. 1999 Jun;65(5):457-9. [2]. Lin Y, et al. Luteolin-4'-O-glucoside and its aglycone, two major flavones of Gnaphalium affine D. Don, resist hyperuricemia and acute gouty arthritis activity in animal models. Phytomedicine. 2018 Mar 1;41:54-61. [3]. Xu T, et al. Glycosylation of luteolin in hydrophilic organic solvents and structure–antioxidant relationships of luteolin glycosides. RSC Advances, 2022, 12(28): 18232-18237.

Density	1.713g/cm3
Boiling Point	814.5ºC at 760 mmHg
Melting Point	210ºC (dec.)
Molecular Formula	C₂₁H₂₀O₁₁
Molecular Weight	448.37700
Flash Point	288.5ºC
Exact Mass	448.10100
PSA	190.28000
Index of Refraction	1.74
InChIKey	UHNXUSWGOJMEFO-RQUKQETFSA-N
SMILES	O=c1cc(-c2ccc(OC3OC(CO)C(O)C(O)C3O)c(O)c2)oc2cc(O)cc(O)c12

Hazard Codes	Xi

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Literature: Kim, Bong-Gyu; Sung, Su Hyun; Jung, Na Ri; Chong, Youhoon; Ahn, Joong-Hoon Journal of Molecular Catalysis B: Enzymatic, 2010 , vol. 63, # 3-4 p. 194 - 199

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Literature: Teslov, L. S.; Koretskaya, L. N. Chemistry of Natural Compounds, 1983 , vol. 19, # 6 p. 749 - 750 Khimiya Prirodnykh Soedinenii, 1983 , # 6 p. 786

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External Id: CHEMBL1025803

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Source: ChEMBL
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Name: HIV Enzyme Data
Source: NIAID
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Source: ChEMBL
Target: N/A
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luteolin-4'-glucoside

3',4',5,7-tetrahydroxyflavone-4'-glucoside

MFCD00017468

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Luteolin-4'-O-glucoside

Use of Luteolin-4'-O-glucoside

Names

Luteolin-4'-O-glucoside Biological Activity

Chemical & Physical Properties

Safety Information

Synthetic Route

Luteolin-4'-O-glucosideBioassay

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.