86770-71-0
86770-71-0 structure
- Name: Benzyl-PEG4-Azido
- Chemical Name: 2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxymethylbenzene
- CAS Number: 86770-71-0
- Molecular Formula: C15H23N3O4
- Molecular Weight: 309.36100
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2016-09-20 18:37:32
- Modify Date: 2024-01-08 09:24:30
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Benzyl-PEG4-Azido is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
| Name | 2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxymethylbenzene |
|---|---|
| Synonyms | 2,5,8,11-Tetraoxatridecane,13-azido-1-phenyl |
| Description | Benzyl-PEG4-Azido is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
| Molecular Formula | C15H23N3O4 |
|---|---|
| Molecular Weight | 309.36100 |
| Exact Mass | 309.16900 |
| PSA | 86.67000 |
| LogP | 2.01606 |
| Hazard Codes | Xi |
|---|
|
~96%
86770-71-0 |
| Literature: THE UNIVERSITY OF UTAH RESEARCH FOUNDATION Patent: WO2007/112100 A2, 2007 ; Location in patent: Page/Page column 103; 130 ; |
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~%
86770-71-0 |
| Literature: Jain, Ahamindra; Huang, Shaw G.; Whitesides, George M. Journal of the American Chemical Society, 1994 , vol. 116, # 12 p. 5057 - 5062 |
|
~%
86770-71-0 |
| Literature: Gartiser, Thierry; Selve, Claude; Mansuy, Laurence; Robert, Alain; Delpuech, Jean-Jacques Journal of Chemical Research, Miniprint, 1984 , # 9 p. 2672 - 2691 |
|
~%
86770-71-0 |
| Literature: Jain, Ahamindra; Huang, Shaw G.; Whitesides, George M. Journal of the American Chemical Society, 1994 , vol. 116, # 12 p. 5057 - 5062 |
|
~%
86770-71-0 |
| Literature: Jain, Ahamindra; Huang, Shaw G.; Whitesides, George M. Journal of the American Chemical Society, 1994 , vol. 116, # 12 p. 5057 - 5062 |
|
~98%
86770-71-0 |
| Literature: Gartiser, Thierry; Selve, Claude; Mansuy, Laurence; Robert, Alain; Delpuech, Jean-Jacques Journal of Chemical Research, Miniprint, 1984 , # 9 p. 2672 - 2691 |
|
~%
86770-71-0 |
| Literature: Gartiser, Thierry; Selve, Claude; Mansuy, Laurence; Robert, Alain; Delpuech, Jean-Jacques Journal of Chemical Research, Miniprint, 1984 , # 9 p. 2672 - 2691 |
| Precursor 6 | |
|---|---|
| DownStream 2 | |
