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100-22-1

100-22-1 structure
100-22-1 structure
  • Name: Wurster's blue
  • Chemical Name: N,N,N',N'-Tetramethyl-1,4-phenylenediamine
  • CAS Number: 100-22-1
  • Molecular Formula: C10H16N2
  • Molecular Weight: 164.25
  • Catalog: Chemical reagent Organic reagent Polyamine
  • Create Date: 2019-01-01 21:18:53
  • Modify Date: 2026-07-15 17:41:36
  • N,N,N′,N′-Tetramethyl-p-phenylenediamine (TMPD) is an redox indicator. N,N,N′,N′-Tetramethyl-p-phenylenediamine can be used for the research of impairment of cell respiration[1][2].
Name N,N,N',N'-Tetramethyl-1,4-phenylenediamine
Synonyms 1,4-bis(dimethylamino)-benzen
4-(Dimethylamino)-N,N-dimethylaniline
N,N,N',N'-4METH-P-PHENDIA 2HCL
N,N,N,N-tetramethyl-P-*phenylenediamine free ba
N,N,N',N'-Tetramethyl-1,4-Benzenediamine
Tetramethyl-p-phenyldiamine
EINECS 202-831-6
N,N,N',N'-TETRAMETHYL-1,4-PHENYLENEDIAMI
N,N,N‘,N‘-Tetramethyl-p-phenylenediamine
N,N,N′,N′-Tetramethyl-1,4-phenylenediamine
MFCD00008309
N,N,N,N-Tetramethyl-p-phenylenediamine
Benzene, 1,4-bis(dimethylamino)
TETRAMETHYLPA-PHENYLENEDIAMINE
n,n,n’,n’-tetramethyl-p-phenylenediamin
N,N,N',N'-Tetramethyl-p-fenylendiamin
N,N,N′,N′-Tetramethyl-p-phenylenediamine
p-Bis(dimethylamino)benzene
N,N,N′,N′-tetramethyl-p-phenylenediamine
1,4-BenzenediaMine, N1,N1,N4,N4-tetraMethyl
1 C10H16N2 N,N,N',N'-Tetramethyl-1,4-phenylenediamine
N,N,N′,N′-tetramethyl-para-phenylenediamine
Amino-2-methyl-123H-tetrazole
n,n,n',n'-tetramethyl-p-phenylenediamine
N,N,N',N'Tetramethyl-p-phenylenediamine(Titration)
N,N,N',N'-tetramethylbenzene-1,4-diamine
N,N,N',N'-TETRAMETHYL-P-*PHENYLENEDIAMIN E FREE BASE
tl85
N1,N1,N4,N4-Tetramethylbenzene-1,4-diamine
tetramethylphenylenediamine
N1,N1,N4,N4-Tetramethyl-1,4-benzenediamine
N,N,N',N'-TetraMethyl-p-phenylenediaMine , powder
N,N,N’,N’-Tetramethyl-p-phenyl
N,N,N',N'-Tetramethyl-1,4-benzenediamine
4-Benzenediamine,N,N,N’,N’-tetramethyl-1
N,N,N',N'-Tetramethyl-p-phenylenediamine
n,n,n’,n’-tetramethyl-p-fenylendiamin
1,4-bis(dimethylamino)benzene
N,N,N’,N’-Tetramethyl-benzene-1,4-diamine
TL 85
1,4-BIS(DIMETHYLAMINO)BENZENE
TMPPD
N,N,NNTetramethyl-p-phenylene- diamine, [1,4-Bis(dimethylamino)benzene
1,4-Benzenediamine, N,N,N,N-tetramethyl
p-Phenylenediamine, N,N,N',N'-tetramethyl
1,4-Bis(dimethylamino)benzene~Wursters Blue
WursterBlue]
1-N,1-N,4-N,4-N-tetramethylbenzene-1,4-diamine
Tetramethyl-p-phenylenediamine
wurster’sblue
n,n,n’,n’-tetramethyl-4-benzenediamine
N,N,N,N-Tetramethyl-1,4-phenylenediamine , N,N,N′,N′-Tetramethyl-p-phenylenediamine
Description N,N,N′,N′-Tetramethyl-p-phenylenediamine (TMPD) is an redox indicator. N,N,N′,N′-Tetramethyl-p-phenylenediamine can be used for the research of impairment of cell respiration[1][2].
Related Catalog
References

[1]. Zhou S, Yao Y, et al. A cytochrome c-enhanced peroxidation reaction with potential use in screening dietary antioxidants. J Pharm Biomed Anal. 2004 Mar 10;34(5):1057-61.  

[2]. Sarti P, et al. Permeability of rat heart myocytes to cytochrome c. Cell Mol Life Sci. 1999 Dec;56(11-12):1061-9.  

Density 1.0±0.1 g/cm3
Boiling Point 260.6±13.0 °C at 760 mmHg
Melting Point 49-51 °C(lit.)
Molecular Formula C10H16N2
Molecular Weight 164.25
Flash Point 104.9±7.7 °C
Exact Mass 164.131348
PSA 6.48000
LogP 2.08
Vapour Pressure 0.0±0.5 mmHg at 25°C
Index of Refraction 1.578
Stability Stable, but may be air or light sensitive. Combustible. Incompatible with acids, acid chlorides, acid anhydrides, oxidizing agents.
Water Solubility slightly in cold, more in hot water

CHEMICAL IDENTIFICATION

RTECS NUMBER :
ST4200000
CHEMICAL NAME :
p-Phenylenediamine, N,N,N',N'-tetramethyl-
CAS REGISTRY NUMBER :
100-22-1
LAST UPDATED :
199701
DATA ITEMS CITED :
8
MOLECULAR FORMULA :
C10-H16-N2
MOLECULAR WEIGHT :
164.28
WISWESSER LINE NOTATION :
1N1&R DN1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
780 mg/m3/10M
TOXIC EFFECTS :
Behavioral - irritability Lungs, Thorax, or Respiration - acute pulmonary edema
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - quail
DOSE/DURATION :
42 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - wild bird species
DOSE/DURATION :
23700 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
Cytogenetic analysis
TEST SYSTEM :
Rodent - hamster Lung
DOSE/DURATION :
10 mg/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 241,175,1990 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3675 No. of Facilities: 14 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 232 (estimated) No. of Female Employees: 130 (estimated)
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302-H312-H332
Precautionary Statements P280
Hazard Codes Xn:Harmful;
Risk Phrases R20/21/22
Safety Phrases S28-S28A
RIDADR UN 2811 6.1/PG 3
WGK Germany 1
RTECS ST4200000
Packaging Group II
Hazard Class 6.1(a)
HS Code 2921519090
HS Code 2921519090
Summary 2921519090. o-, m-, p-phenylenediamine, diaminotoluenes, and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:17.0%. . MFN tariff:6.5%. General tariff:30.0%
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