21637-25-2
21637-25-2 structure
- Name: Isoquercitrin
- Chemical Name: quercetin 3-O-β-D-glucofuranoside
- CAS Number: 21637-25-2
- Molecular Formula: C21H20O12
- Molecular Weight: 464.376
- Catalog: Biochemical Plant extracts
- Create Date: 2018-07-07 20:19:31
- Modify Date: 2026-07-01 10:29:08
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Isoquercitrin is an effective antioxidant and an eosinophilic inflammation suppressor.
| Name | quercetin 3-O-β-D-glucofuranoside |
|---|---|
| Synonyms |
Isotrifoliin
QUERCETIN-3-O-BETA-GLUCOPYRANOSIDE 3,3’,4’,5,7-pentahydroxy-flavon3-beta-d-glucofuranoside ISOQUERCITRIN (DISCONTINUED)(SH) Rutoside Impurity A 3-(((2S,3R,4R,5R)-5-((R)-1,2-Dihydroxyethyl)-3,4-dihydroxytetrahydrofuran-2-yl)oxy)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one soquercitrin trifoliin Isoquercitrin (Isoquercitroside Isoquercitrin / quercetin glycoside 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-3-(β-D-glucofuranosyloxy)-5,7-dihydroxy Quercetin 3-b-D-glucoside QUERCETIN-3-O-BETA-D-GLUCOPYRANOSIDE quercetin 3-O-β-D-glucopyranoside Quercetin 3β-O-glucoside Quercetin 3 quercetin3-O-β-D-glucofuranoside ISOTRIFOLIN Quercetin 3-O-glucofuranoside QUERCETIN-3-GLUCOSIDE ISOQUERCITRIN b 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yl β-D-glucopyranoside 2-(3,4-dihydroxyphenyl)-3-(β-D-glucofuranosyloxy) 3-(β-D-Glucofuranosyloxy)-5,7-dihydroxy-2-(3,4-dihydroxyphenyl)-4H-1-benzopyran-4-one quercetin-3-glucoside 3-O-β-D-Glucopyranosylquercetin Isoquercitroside Quercetin-3-O-β-glucopyranoside Cocaflavin ISOQUERCITROSIDE Isoquercetrin Quercetin 3-O-glucoside QUERCETIN 3-O-GLUCOPYRANOSIDE 2-(3,4-Dihidroxyphenyl)-3-(beta-D-glucofuranosyloxy)-5,7-dihydroxy-4H-1-benzopyran-4-one Quercetin 3-β-D-glucoside ,>= quercetin 3-O-β-D-glucoside Quercitin-3-beta-D-glucofuranoside Hirsutrin isotrifoliin 2-(3,4-dihydroxyphenyl)-3-(β-D-glucofuranosyloxy)-5,7-dihyd 3,3',4',5,7-Pentahydroxyflavone 3-b-D-glucofuranoside Quercetin-3-β-glucopyranoside Quercetin 3-β-O-glucoside 2-(3,4-Dihydroxyphenyl)-3-(b-D-glucofuranosyloxy)-5,7-dihydroxy-4H-1-benzopyran-4-one 3,3',4',5,7-Pentahydroxyflavone 3-β-glucoside ningenin-7-O-β-D-glucoside Quercetin 3-glucofranoside Quercetin 3-β-D-glucoside, (HPLC) Quercetin 3-O-β-glucoside 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yl β-D-glucofuranoside ISOQUERCITRIN hplc ISOQUERCETIN ISOQUERCITRIN Quercetin 3-β-glucoside 4h-1-benzopyran-4-one,2-(3,4-dihydroxyphenyl)-3-(beta-d-glucofuranosyloxy)-5 2,4-Dichlorobenzyl Alcohol Impurity 8 (3,4-Dichlorobenzyl Mercaptan) 2-(3,4-dihydroxyphenyl)-3-(β-D-glucofuranosyloxy)-5,7-dihydroxy-4H-1-benzopyran-4-one Quercetin 3-Oxyglucoside Isopseudopsoralen isopseudopsoralene QUERCETIN-3-BETA-D-GLUCOSIDE 3,4,5',7'-TETRAHYDROXYFLAVONE-3'-GLUCOSIDE Isoquercitroside CRS Quercetin 3-β-D-glucoside 2-(3,4-Hihydroxyphenyl)-3-(beta-D-glucofuranosyloxy)-5,7-dihydroxy-4H-1-benzopyran-4-one 2-(3,4-dihydroxyphenyl)-3-(beta-D-glucofuranosyloxy)-5,7-dihydroxy-4H-1-benzopyran-4-one D-glucofuranosyloxy)-5,7-dihydroxy-4H-1-benzopyran-4-one Quercetin glucoside Quercitin-3'-O- glucofuranoside Quercetin-3-O-β-D-glucoside 3,3',4',5,7-PENTAHYDROXYFLAVONE-3-BETA-GLUCOSIDE isopseudosporalen 7-dihydroxy Quercetin 3-D-glucoside QUERCETIN-3-O-B-GLUCOPYRANOSIDE isoquercetin 3,3’,4’,5,7-pentahydroxyflavone3-beta-d-glucofuranoside Isoquercitrin (Synonyms: Isoquercitroside QUERCETIN-3-O-B-D-GLUCOFURANOSIDE quercetin 3-O-beta-D-glucofuranoside 3-[[(2S,3R,4R,5R)-5-[(1R)-1,2-dihydroxyethyl]-3,4-dihydroxy-2-oxolanyl]oxy]-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-1-benzopyran-4-one Quercetin-3-O-glucoside Quercetin 3-β-D-glucoside,3,3′,4′,5,7-Pentahydroxyflavone 3-β-glucoside, Isoquercitrin QUERCETIN-3-O-GLUCOSIDE Quercetin 3-β-D-gluc C05623 Quercetin 3-O-glucopyranoside |
| Description | Isoquercitrin is an effective antioxidant and an eosinophilic inflammation suppressor. |
|---|---|
| Related Catalog | |
| In Vitro | Isoquercitrin occurs widely in plants.10 μM of Isoquercitrin of the seven compounds partially but significantly blunt the negative effect of H2O2 on RGC-5 cells, as the viability of cells in the presence of H2O2 is increased from approximately 63% to 83% and 90% at 10 and 50 μM, respectively. Indeed, 50 μM Isoquercitrin is more effective as a neuroprotectant than the same concentration of EGCG[1]. |
| In Vivo | In animals receiving Isoquercitrin or quercetin, eosinophil counts are lower in the BALF, blood and lung parenchyma. Neutrophil counts in blood and IL-5 levels in lung homogenate are lower only in Isoquercitrin-treated mice. No alterations in mononuclear cell numbers were observed[2]. |
| Animal Admin | Mice[2] BALB/c mice are immunized (ovalbumin/aluminum hydroxide, s.c.), followed by two intranasal ovalbumin challenges. From day 18 to day 22 after the first immunization, the mice receive daily gavages of Isoquercitrin (15 mg/kg) or quercetin (10 mg/kg). Dexamethasone (1 mg/kg, s. c.) is administered as a positive control. Leucocytes are analyzed in bronchoalveolar lavage fluid (BALF), blood and pulmonary parenchyma at 24 h after the last ovalbumin challenge. Interleukin-5 (IL-5) is analyzed in BALF and lung homogenates[2]. |
| References |
| Density | 1.9±0.1 g/cm3 |
|---|---|
| Boiling Point | 872.6±65.0 °C at 760 mmHg |
| Melting Point | 225-227° |
| Molecular Formula | C21H20O12 |
| Molecular Weight | 464.376 |
| Flash Point | 307.5±27.8 °C |
| Exact Mass | 464.095490 |
| PSA | 210.51000 |
| LogP | 1.75 |
| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
| Index of Refraction | 1.803 |
| Storage condition | −20°C |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATAMUTATION DATA
|
| Safety Phrases | 24/25 |
|---|---|
| RIDADR | UN 2811 |
| WGK Germany | 3 |
| RTECS | LK8960000 |
