Top Suppliers:I want be here
Related CAS#:
254886-77-6 99119-69-4
101236-50-4 99119-73-0
101236-51-5 99217-63-7
254886-72-1 254886-76-5
99119-72-9 99217-64-8
2228211-89-8 2648961-15-1
2172598-15-9 2172009-76-4
2172618-78-7 2171348-96-0
1337602-14-8 2414672-95-8
2710295-81-9 2839207-56-4

254886-77-6

254886-77-6 structure
254886-77-6 structure
  • Name: Kushenol X
  • Chemical Name: Kushenol X
  • CAS Number: 254886-77-6
  • Molecular Formula: C25H28O7
  • Molecular Weight: 440.486
  • Catalog: Natural product Flavonoids
  • Create Date: 2016-11-07 04:24:06
  • Modify Date: 2025-08-22 15:14:48
  • Kushenol X, a flavonoid compound isolated from the roots of Sophora flavescens. Kushenol X is a potent β-glucuronidase and human carboxylesterase 2 (hCE2) inhibitor with IC50s of 2.07 μM and 3.05 μM, respectively[1][2].
Name Kushenol X
Synonyms 4H-1-Benzopyran-4-one, 2-(2,4-dihydroxyphenyl)-2,3-dihydro-3,5,7-trihydroxy-8-[5-methyl-2-(1-methylethenyl)-4-hexen-1-yl]-, (2R,3R)-
(2R,3R)-2-(2,4-Dihydroxyphenyl)-3,5,7-trihydroxy-8-[(2R)-2-isopropenyl-5-methyl-4-hexen-1-yl]-2,3-dihydro-4H-chromen-4-one
Kushenol X
(2R,3R)-2-(2,4-Dihydroxyphenyl)-3,5,7-trihydroxy-8-(2-isopropenyl-5-methyl-4-hexen-1-yl)-2,3-dihydro-4H-chromen-4-one
4H-1-Benzopyran-4-one, 2-(2,4-dihydroxyphenyl)-2,3-dihydro-3,5,7-trihydroxy-8-[(2R)-5-methyl-2-(1-methylethenyl)-4-hexen-1-yl]-, (2R,3R)-
Description Kushenol X, a flavonoid compound isolated from the roots of Sophora flavescens. Kushenol X is a potent β-glucuronidase and human carboxylesterase 2 (hCE2) inhibitor with IC50s of 2.07 μM and 3.05 μM, respectively[1][2].
Related Catalog
Target

IC50: 2.07 μM (β-glucuronidase)[1] and 3.05 μM (Human carboxylesterase 2 (hCE2))[2]

References

[1]. Cheng-Peng Sun, et al. The study of inhibitory effect of natural flavonoids toward β-glucuronidase and interaction of flavonoids with β-glucuronidase. Int J Biol Macromol. 2020 Jan 15;143:349-358.

[2]. Sha-Sha Song, et al. Flavonoids as human carboxylesterase 2 inhibitors: Inhibition potentials and molecular docking simulations. Int J Biol Macromol. 2019 Jun 15;131:201-208.
Density 1.3±0.1 g/cm3
Boiling Point 699.6±55.0 °C at 760 mmHg
Molecular Formula C25H28O7
Molecular Weight 440.486
Flash Point 238.8±25.0 °C
Exact Mass 440.183502
PSA 127.45000
LogP 5.74
Vapour Pressure 0.0±2.3 mmHg at 25°C
Index of Refraction 1.640
Hazard Codes Xi
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Chemsrc provides CAS#:254886-77-6 MSDS, density, melting point, boiling point, structure, formula, molecular weight, synthetic route, etc.
title: CAS No. 254886-77-6 | Chemsrc address: https://m.chemsrc.com/en/baike/642067.html

Home | MSDS/SDS Database Search | Journals | Product Classification | Biologically Active Compounds | Selling Leads | About Us | Disclaimer

Copyright © 2024 ChemSrc All Rights Reserved