- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: 2-Cyanopyrimidine
- Price: Check
- Purity: 98.0%
- Stocking Period: 10 Day
- Contact: Yang
- Email: sales@echemcloud.com
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: 2-Cyanopyrimidine
- Price: ￥198.0/25g ￥68.0/5g
- Purity: 95.0%
- Stocking Period: Inquiry
- Contact: Liu jia
- Email: 2130147988@qq.com
- DC Chemicals Limited
- China
- Product Name: 2-cyano-Pyrimidine
- Price: $150.0/100mg $300.0/250mg $600.0/1g
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
- ShangHai DC Chemicals Co.,Ltd
- China
- Product Name: 2-cyano-Pyrimidine
- Price: ￥Inquiry/1g
- Purity: 98.9%
- Stocking Period: 1 Day
- Contact: Tony Lai
- Email: order@dcchemicals.com
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: 2-Cyanopyrimidine
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
- Email: enquiry@dycnchem.com
- Henan Tianfu Chemical Co., Ltd.
- China
- Product Name: 2-Cyanopyrimidine
- Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
- Purity: 99.0%
- Stocking Period: Inquiry
- Contact: Anson
- Email: info@tianfuchem.com
- Zhongshan Xingrui Chemical Co. , Ltd.
- China
- Product Name: 2-Cyanopyrimidine
- Price: ￥Inquiry/25kg
- Purity: 99.0%
- Stocking Period: Inquiry
- Contact: Wang Jie
- Email: 3096638339@qq.com
14080-23-0
14080-23-0 structure
- Name: 2-Cyanopyrimidine
- Chemical Name: 2-Cyanopyrimidine
- CAS Number: 14080-23-0
- Molecular Formula: C5H3N3
- Molecular Weight: 105.097
- Catalog: Pharmaceutical intermediate Heterocyclic compound Pyrimidine compound Cyanopyrimidine
- Create Date: 2018-05-25 08:00:00
- Modify Date: 2025-08-21 20:39:37
-
2-Cyanopyrimidine is a potent and non-selective cysteine protease cathepsin K inhibitor with an IC50 of 170 nM. 2-Cyanopyrimidine is used for osteoporos[1].
| Name | 2-Cyanopyrimidine |
|---|---|
| Synonyms |
2-Cyanopyrimidine
NaMe: 2-CyanopyriMidine Pyrimidin-2-carbonitril 2-Cynopyrimidine 2-CPY pyrimidin-2-carbonitrile MFCD00160513 2CPM 2-Pyrimidinecarbonitrile Pyrimidine-2-carbonitrile 2-cyanpyrimidine 2-pyrimidinenitrile |
| Description | 2-Cyanopyrimidine is a potent and non-selective cysteine protease cathepsin K inhibitor with an IC50 of 170 nM. 2-Cyanopyrimidine is used for osteoporos[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 170 nM (cysteine protease cathepsin K)[1] |
| In Vitro | 2-Cyanopyrimidine is a 2-cyano-4-cyclohexylamino-pyrimidine derivative. Cathepsin K is a lysosomal cysteine protease[1]. |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 250.7±23.0 °C at 760 mmHg |
| Melting Point | 40-44 °C(lit.) |
| Molecular Formula | C5H3N3 |
| Molecular Weight | 105.097 |
| Flash Point | 97.2±7.8 °C |
| Exact Mass | 105.032700 |
| PSA | 49.57000 |
| LogP | -0.31 |
| Vapour Pressure | 0.0±0.5 mmHg at 25°C |
| Index of Refraction | 1.541 |
| Symbol |
GHS06 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H301-H317 |
| Precautionary Statements | P280-P301 + P310 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Faceshields;Gloves |
| Hazard Codes | Xn:Harmful |
| Risk Phrases | R22;R37/38;R41;R43 |
| Safety Phrases | S26-S36/37/39 |
| RIDADR | 3276 |
| WGK Germany | 3 |
| HS Code | 2933599090 |
| HS Code | 2933599090 |
|---|---|
| Summary | 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |