117204-81-6

117204-81-6 structure

Name: Sophora-iso-flavone A
Chemical Name: 5,5',7-trihydroxy-2',2'-dimethyl-2'H,4H-[3,8'-bichromen]-4-one
CAS Number: 117204-81-6
Molecular Formula: C₂₀H₁₆O₆
Molecular Weight: 352.34
Catalog: Natural product Flavonoids
Create Date: 2016-10-29 18:04:21
Modify Date: 2025-08-20 00:54:11
Sophoraisoflavone A (Allolicoisoflavone B) is a nature product that could be isolated from Glycyrrhiza inflate. Sophoraisoflavone A is a potent protein tyrosine phosphatase 1B (PTP1B) inhibitor with an IC50 value of 0.80 μM. Sophoraisoflavone A can be used in research of inflammation[1].

Name	5,5',7-trihydroxy-2',2'-dimethyl-2'H,4H-[3,8'-bichromen]-4-one
Synonyms	4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-(5-hydroxy-2,2-dimethyl-2H-1-benzopyran-8-yl)- Sophora-iso-flavone A 5,5',7-Trihydroxy-2',2'-dimethyl-2'H,4H-3,8'-bichromen-4-one

Description	Sophoraisoflavone A (Allolicoisoflavone B) is a nature product that could be isolated from Glycyrrhiza inflate. Sophoraisoflavone A is a potent protein tyrosine phosphatase 1B (PTP1B) inhibitor with an IC50 value of 0.80 μM. Sophoraisoflavone A can be used in research of inflammation[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphatase Research Areas >> Inflammation/Immunology
References	[1]. Lin Y, et, al. Screening for bioactive natural products from a 67-compound library of Glycyrrhiza inflata. Bioorg Med Chem. 2017 Jul 15;25(14):3706-3713.