Sophora-iso-flavone A

Modify Date: 2024-01-02 18:42:14

Sophora-iso-flavone A Structure
Sophora-iso-flavone A structure
Common Name Sophora-iso-flavone A
CAS Number 117204-81-6 Molecular Weight 352.34
Density 1.4±0.1 g/cm3 Boiling Point 611.2±55.0 °C at 760 mmHg
Molecular Formula C20H16O6 Melting Point 235-237℃
MSDS N/A Flash Point 223.9±25.0 °C

 Use of Sophora-iso-flavone A


Sophoraisoflavone A (Allolicoisoflavone B) is a nature product that could be isolated from Glycyrrhiza inflate. Sophoraisoflavone A is a potent protein tyrosine phosphatase 1B (PTP1B) inhibitor with an IC50 value of 0.80 μM. Sophoraisoflavone A can be used in research of inflammation[1].

 Names

Name 5,5',7-trihydroxy-2',2'-dimethyl-2'H,4H-[3,8'-bichromen]-4-one
Synonym More Synonyms

 Sophora-iso-flavone A Biological Activity

Description Sophoraisoflavone A (Allolicoisoflavone B) is a nature product that could be isolated from Glycyrrhiza inflate. Sophoraisoflavone A is a potent protein tyrosine phosphatase 1B (PTP1B) inhibitor with an IC50 value of 0.80 μM. Sophoraisoflavone A can be used in research of inflammation[1].
Related Catalog
References

[1]. Lin Y, et, al. Screening for bioactive natural products from a 67-compound library of Glycyrrhiza inflata. Bioorg Med Chem. 2017 Jul 15;25(14):3706-3713.  

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 611.2±55.0 °C at 760 mmHg
Melting Point 235-237℃
Molecular Formula C20H16O6
Molecular Weight 352.34
Flash Point 223.9±25.0 °C
Exact Mass 352.094696
PSA 100.13000
LogP 5.33
Vapour Pressure 0.0±1.8 mmHg at 25°C
Index of Refraction 1.683

 Synonyms

4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-(5-hydroxy-2,2-dimethyl-2H-1-benzopyran-8-yl)-
Sophora-iso-flavone A
5,5',7-Trihydroxy-2',2'-dimethyl-2'H,4H-3,8'-bichromen-4-one
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