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207347-42-0

207347-42-0 structure
207347-42-0 structure
  • Name: N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite
  • Chemical Name: 3'-da cep
  • CAS Number: 207347-42-0
  • Molecular Formula: C47H52N7O7P
  • Molecular Weight: 857.93
  • Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
  • Create Date: 2017-12-31 15:12:56
  • Modify Date: 2026-07-15 16:11:26
  • N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].
Name 3'-da cep
Synonyms 3'-Deoxy-A(Bz)-2'-phosphoramidite
N6-Benzoyl-5'-O-DMT-3'-deoxyadenosine 2'-CE phosphoraMidite
N6-Benzoyl-3'-deoxy-5'-O-DMT-adenosine 2'-CE phosphoramidite
(2R,3R,5S)-2-(6-Benzamido-9H-purin-9-yl)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)tetrahydrofuran-3-yl (2-cyanoethyl) diiSopropylphosphoramidite
N6-Benzoyl-5'-O-DMT-3'-deoxyadenosine 2'-CE phosphoramidite
3'-dAC
N6-Bz-5’-O-DMTr-3’-deoxyadenosine-2’-O-CED-phosphoramidite,3’-Deoxy-A(Bz)-2’-phosphoramidite
N6-benzoyl-3'-deoxy-5'-O-(4,4'-dimethoxytrityl)adenosine 2'-(2-cyanoethyl diisopropylphosphoramidite)
Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-deoxy-, 2'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
N6-Bz-5’-O-DMTr-3’-dA-2’-O-CED-phosphoramidite
3'-dA
3'-da-CE Phosphoramidite
N6-Bz-5''-O-DMTr-3''-deoxyadenosine-2''-O-CED-phosphoramidite
3'-DA C
N6-BENZOYL-5'-O-(4,4'-DIMETHOXYTRITYL)-3'-DEOXYADENOSINE, 2'-[(2-CYANOETHYL)-(N,N-DIISOPROPYL)]PHOSPHORAMIDITE
Description N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].
Related Catalog
References

[1]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.  

Molecular Formula C47H52N7O7P
Molecular Weight 857.93
Exact Mass 857.36700
PSA 168.70000
LogP 9.12618
102691-36-1 structure

102691-36-1

84138-86-3 structure

84138-86-3

~91%

207347-42-0 structure

207347-42-0

Literature: Charubala, Ramamurthy; Pfleidere, Wolfgang; Suhadolnik, Robert J.; Iacono, Kathryn T.; Muto, Nicholas F.; Homan, Joseph W.; Martinand-Mari, Camille; Horvath, Susan E.; Henderson, Earl E.; Steele, Amber; Rogers, Thomas J. Helvetica Chimica Acta, 2002 , vol. 85, # 8 p. 2284 - 2299
124482-92-4 structure

124482-92-4

84138-86-3 structure

84138-86-3

~67%

207347-42-0 structure

207347-42-0

Literature: Arslan, Tuncer; Abraham, Anil T.; Hecht, Sidney M. Nucleosides and Nucleotides, 1998 , vol. 17, # 1-3 p. 515 - 530
40615-36-9 structure

40615-36-9

~%

207347-42-0 structure

207347-42-0

Literature: Arslan, Tuncer; Abraham, Anil T.; Hecht, Sidney M. Nucleosides and Nucleotides, 1998 , vol. 17, # 1-3 p. 515 - 530
73-03-0 structure

73-03-0

~%

207347-42-0 structure

207347-42-0

Literature: Charubala, Ramamurthy; Pfleidere, Wolfgang; Suhadolnik, Robert J.; Iacono, Kathryn T.; Muto, Nicholas F.; Homan, Joseph W.; Martinand-Mari, Camille; Horvath, Susan E.; Henderson, Earl E.; Steele, Amber; Rogers, Thomas J. Helvetica Chimica Acta, 2002 , vol. 85, # 8 p. 2284 - 2299
98-88-4 structure

98-88-4

~%

207347-42-0 structure

207347-42-0

Literature: Charubala, Ramamurthy; Pfleidere, Wolfgang; Suhadolnik, Robert J.; Iacono, Kathryn T.; Muto, Nicholas F.; Homan, Joseph W.; Martinand-Mari, Camille; Horvath, Susan E.; Henderson, Earl E.; Steele, Amber; Rogers, Thomas J. Helvetica Chimica Acta, 2002 , vol. 85, # 8 p. 2284 - 2299
76902-49-3 structure

76902-49-3

~%

207347-42-0 structure

207347-42-0

Literature: Arslan, Tuncer; Abraham, Anil T.; Hecht, Sidney M. Nucleosides and Nucleotides, 1998 , vol. 17, # 1-3 p. 515 - 530
60855-35-8 structure

60855-35-8

~%

207347-42-0 structure

207347-42-0

Literature: Arslan, Tuncer; Abraham, Anil T.; Hecht, Sidney M. Nucleosides and Nucleotides, 1998 , vol. 17, # 1-3 p. 515 - 530
207347-41-9 structure

207347-41-9

~%

207347-42-0 structure

207347-42-0

Literature: Arslan, Tuncer; Abraham, Anil T.; Hecht, Sidney M. Nucleosides and Nucleotides, 1998 , vol. 17, # 1-3 p. 515 - 530
207347-40-8 structure

207347-40-8

~%

207347-42-0 structure

207347-42-0

Literature: Arslan, Tuncer; Abraham, Anil T.; Hecht, Sidney M. Nucleosides and Nucleotides, 1998 , vol. 17, # 1-3 p. 515 - 530
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