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207347-42-0

207347-42-0 structure
207347-42-0 structure
  • Name: N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite
  • Chemical Name: 3'-da cep
  • CAS Number: 207347-42-0
  • Molecular Formula: C47H52N7O7P
  • Molecular Weight: 857.93
  • Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
  • Create Date: 2017-12-31 15:12:56
  • Modify Date: 2024-01-02 21:27:47
  • N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

Name 3'-da cep
Synonyms N6-Benzoyl-5'-O-DMT-3'-deoxyadenosine 2'-CE phosphoramidite
Description N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].
Related Catalog
References

[1]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.  

Molecular Formula C47H52N7O7P
Molecular Weight 857.93
Exact Mass 857.36700
PSA 168.70000
LogP 9.12618

~91%

207347-42-0 structure

207347-42-0

Literature: Charubala, Ramamurthy; Pfleidere, Wolfgang; Suhadolnik, Robert J.; Iacono, Kathryn T.; Muto, Nicholas F.; Homan, Joseph W.; Martinand-Mari, Camille; Horvath, Susan E.; Henderson, Earl E.; Steele, Amber; Rogers, Thomas J. Helvetica Chimica Acta, 2002 , vol. 85, # 8 p. 2284 - 2299

~67%

207347-42-0 structure

207347-42-0

Literature: Arslan, Tuncer; Abraham, Anil T.; Hecht, Sidney M. Nucleosides and Nucleotides, 1998 , vol. 17, # 1-3 p. 515 - 530

~%

207347-42-0 structure

207347-42-0

Literature: Arslan, Tuncer; Abraham, Anil T.; Hecht, Sidney M. Nucleosides and Nucleotides, 1998 , vol. 17, # 1-3 p. 515 - 530

~%

207347-42-0 structure

207347-42-0

Literature: Charubala, Ramamurthy; Pfleidere, Wolfgang; Suhadolnik, Robert J.; Iacono, Kathryn T.; Muto, Nicholas F.; Homan, Joseph W.; Martinand-Mari, Camille; Horvath, Susan E.; Henderson, Earl E.; Steele, Amber; Rogers, Thomas J. Helvetica Chimica Acta, 2002 , vol. 85, # 8 p. 2284 - 2299

~%

207347-42-0 structure

207347-42-0

Literature: Charubala, Ramamurthy; Pfleidere, Wolfgang; Suhadolnik, Robert J.; Iacono, Kathryn T.; Muto, Nicholas F.; Homan, Joseph W.; Martinand-Mari, Camille; Horvath, Susan E.; Henderson, Earl E.; Steele, Amber; Rogers, Thomas J. Helvetica Chimica Acta, 2002 , vol. 85, # 8 p. 2284 - 2299

~%

207347-42-0 structure

207347-42-0

Literature: Arslan, Tuncer; Abraham, Anil T.; Hecht, Sidney M. Nucleosides and Nucleotides, 1998 , vol. 17, # 1-3 p. 515 - 530

~%

207347-42-0 structure

207347-42-0

Literature: Arslan, Tuncer; Abraham, Anil T.; Hecht, Sidney M. Nucleosides and Nucleotides, 1998 , vol. 17, # 1-3 p. 515 - 530

~%

207347-42-0 structure

207347-42-0

Literature: Arslan, Tuncer; Abraham, Anil T.; Hecht, Sidney M. Nucleosides and Nucleotides, 1998 , vol. 17, # 1-3 p. 515 - 530

~%

207347-42-0 structure

207347-42-0

Literature: Arslan, Tuncer; Abraham, Anil T.; Hecht, Sidney M. Nucleosides and Nucleotides, 1998 , vol. 17, # 1-3 p. 515 - 530