N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite

Modify Date: 2024-01-02 21:27:47

N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite Structure
N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite structure
 Common Name N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite
CAS Number 207347-42-0 Molecular Weight 857.93
Density N/A Boiling Point N/A
Molecular Formula C47H52N7O7P Melting Point N/A
MSDS N/A Flash Point N/A

 Use of N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite


N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

 Names

Name 3'-da cep
Synonym More Synonyms

  Biological Activity

Description N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].
Related Catalog
References

[1]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.  

 Chemical & Physical Properties

Molecular Formula C47H52N7O7P
Molecular Weight 857.93
Exact Mass 857.36700
PSA 168.70000
LogP 9.12618

 Synthetic Route

2-Cyanoethyltetraisopropylphosphorodiamidite structure

2-Cyanoethyltet...

CAS#:102691-36-1
N6-BENZOYL-5'-O-(DIMETHOXYTRITYL)-3'-DEOXYADENOSINE structure

N6-BENZOYL-5'-O...

CAS#:84138-86-3

~91%

N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite Structure

N6-Bz-5'-O-DMTr...

CAS#:207347-42-0
Literature: Charubala, Ramamurthy; Pfleidere, Wolfgang; Suhadolnik, Robert J.; Iacono, Kathryn T.; Muto, Nicholas F.; Homan, Joseph W.; Martinand-Mari, Camille; Horvath, Susan E.; Henderson, Earl E.; Steele, Amber; Rogers, Thomas J. Helvetica Chimica Acta, 2002 , vol. 85, # 8 p. 2284 - 2299
2-cyanoethyl N,N- diisopropylchlorophosphoramidite structure

2-cyanoethyl N,...

CAS#:124482-92-4
N6-BENZOYL-5'-O-(DIMETHOXYTRITYL)-3'-DEOXYADENOSINE structure

N6-BENZOYL-5'-O...

CAS#:84138-86-3

~67%

N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite Structure

N6-Bz-5'-O-DMTr...

CAS#:207347-42-0
Literature: Arslan, Tuncer; Abraham, Anil T.; Hecht, Sidney M. Nucleosides and Nucleotides, 1998 , vol. 17, # 1-3 p. 515 - 530
4,4'-Dimethoxytrityl chloride structure

4,4'-Dimethoxyt...

CAS#:40615-36-9

~%

N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite Structure

N6-Bz-5'-O-DMTr...

CAS#:207347-42-0
Literature: Arslan, Tuncer; Abraham, Anil T.; Hecht, Sidney M. Nucleosides and Nucleotides, 1998 , vol. 17, # 1-3 p. 515 - 530
Cordycepin structure

Cordycepin

CAS#:73-03-0

~%

N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite Structure

N6-Bz-5'-O-DMTr...

CAS#:207347-42-0
Literature: Charubala, Ramamurthy; Pfleidere, Wolfgang; Suhadolnik, Robert J.; Iacono, Kathryn T.; Muto, Nicholas F.; Homan, Joseph W.; Martinand-Mari, Camille; Horvath, Susan E.; Henderson, Earl E.; Steele, Amber; Rogers, Thomas J. Helvetica Chimica Acta, 2002 , vol. 85, # 8 p. 2284 - 2299
Benzoyl chloride structure

Benzoyl chloride

CAS#:98-88-4

~%

N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite Structure

N6-Bz-5'-O-DMTr...

CAS#:207347-42-0
Literature: Charubala, Ramamurthy; Pfleidere, Wolfgang; Suhadolnik, Robert J.; Iacono, Kathryn T.; Muto, Nicholas F.; Homan, Joseph W.; Martinand-Mari, Camille; Horvath, Susan E.; Henderson, Earl E.; Steele, Amber; Rogers, Thomas J. Helvetica Chimica Acta, 2002 , vol. 85, # 8 p. 2284 - 2299
N6-BENZOYL-3'-DEOXYADENOSINE structure

N6-BENZOYL-3'-D...

CAS#:76902-49-3

~%

N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite Structure

N6-Bz-5'-O-DMTr...

CAS#:207347-42-0
Literature: Arslan, Tuncer; Abraham, Anil T.; Hecht, Sidney M. Nucleosides and Nucleotides, 1998 , vol. 17, # 1-3 p. 515 - 530
N-(9-trimethylsilylpurin-6-yl)benzamide structure

N-(9-trimethyls...

CAS#:60855-35-8

~%

N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite Structure

N6-Bz-5'-O-DMTr...

CAS#:207347-42-0
Literature: Arslan, Tuncer; Abraham, Anil T.; Hecht, Sidney M. Nucleosides and Nucleotides, 1998 , vol. 17, # 1-3 p. 515 - 530
N/A structure

N/A

CAS#:207347-41-9

~%

N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite Structure

N6-Bz-5'-O-DMTr...

CAS#:207347-42-0
Literature: Arslan, Tuncer; Abraham, Anil T.; Hecht, Sidney M. Nucleosides and Nucleotides, 1998 , vol. 17, # 1-3 p. 515 - 530
(R)-1-((2S,4R,5R)-4-acetoxy-5-(6-benzamido-9H-purin-9-yl)tetrahydrofuran-2-yl)ethane-1,2-diyl diacetate structure

(R)-1-((2S,4R,5...

CAS#:207347-40-8

~%

N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite Structure

N6-Bz-5'-O-DMTr...

CAS#:207347-42-0
Literature: Arslan, Tuncer; Abraham, Anil T.; Hecht, Sidney M. Nucleosides and Nucleotides, 1998 , vol. 17, # 1-3 p. 515 - 530

 Synonyms

N6-Benzoyl-5'-O-DMT-3'-deoxyadenosine 2'-CE phosphoramidite
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Chemsrc provides CAS#:207347-42-0 MSDS, density, melting point, boiling point, structure, etc. Its name is N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite>> amp version: N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite

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