71119-11-4

71119-11-4 structure
71119-11-4 structure
  • Name: Bucindolol
  • Chemical Name: 2-[2-hydroxy-3-[[1-(1H-indol-3-yl)-2-methylpropan-2-yl]amino]propoxy]benzonitrile
  • CAS Number: 71119-11-4
  • Molecular Formula: C22H25N3O2
  • Molecular Weight: 363.453
  • Catalog: Signaling Pathways GPCR/G Protein Adrenergic Receptor
  • Create Date: 2018-02-12 08:00:00
  • Modify Date: 2025-08-25 19:38:04
  • Bucindolol is a β1-adrenergic receptor blocker, with intrinsic sympathomimetic activity, used in the research of heart failure[1].

Name 2-[2-hydroxy-3-[[1-(1H-indol-3-yl)-2-methylpropan-2-yl]amino]propoxy]benzonitrile
Synonyms Benzonitrile, 2-[2-hydroxy-3-[[2-(1H-indol-3-yl)-1,1-dimethylethyl]amino]propoxy]-
2-(2-Hydroxy-3-{[1-(1H-indol-3-yl)-2-methylpropan-2-yl]amino}propoxy)benzonitrile
Bucindolol
2-(2-Hydroxy-3-{[1-(1H-indol-3-yl)-2-methyl-2-propanyl]amino}propoxy)benzonitrile
2-[2-Hydroxy-3-[[2-(1H-indol-3-yl)-1,1-dimethylethyl]amino]propoxy]benzonitrile
o-(2-Hydroxy-3-((2-indol-3-yl-1,1-dimethylethyl)amino)propoxy)benzonitrile
Density 1.2±0.1 g/cm3
Boiling Point 605.3±55.0 °C at 760 mmHg
Molecular Formula C22H25N3O2
Molecular Weight 363.453
Flash Point 319.9±31.5 °C
Exact Mass 363.194672
PSA 81.07000
LogP 3.19
Vapour Pressure 0.0±1.8 mmHg at 25°C
Index of Refraction 1.632

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DI4637550
CHEMICAL NAME :
Benzonitrile, 2-(2-hydroxy-3-((2-(1H-indol-3-yl)-1,1-dimethylethyl) amino)propoxy)-
CAS REGISTRY NUMBER :
71119-11-4
LAST UPDATED :
199712
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C22-H25-N3-O2
MOLECULAR WEIGHT :
363.50

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
20200 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EPXXDW European Patent Application. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #0065295
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
9600 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EPXXDW European Patent Application. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #0065295
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