147403-65-4

147403-65-4 structure

Name: 2-Ethoxy-1-[[2'-[(hydroxyamino)iminomethyl][1,1'-biphenyl]-4-yl]methyl]-1H-benzimidazole-7-carboxylic acid methyl ester
Chemical Name: methyl 2-ethoxy-3-[[4-[2-[(Z)-N'-hydroxycarbamimidoyl]phenyl]phenyl]methyl]benzimidazole-4-carboxylate
CAS Number: 147403-65-4
Molecular Formula: C₂₅H₂₄N₄O₄
Molecular Weight: 444.483
Create Date: 2018-12-24 14:24:25
Modify Date: 2026-07-08 13:16:35

Name	methyl 2-ethoxy-3-[[4-[2-[(Z)-N'-hydroxycarbamimidoyl]phenyl]phenyl]methyl]benzimidazole-4-carboxylate
Synonyms	2-Ethoxy-1-[[2'-[(hydroxyamino)iminomethyl][1 2-ethoxy-1-((2'-((hydroxyamino)iminomethyl)(1,1'-biphenyl)-4 methyl 2-ethoxy-1-((2'-(N'-hydroxycarbamimidoyl)biphenyl-4-yl)methyl)-1H-benzo[d]imidazole-7-carboxylate methyl 2-ethoxy-3-[[4-[2-[(Z)-N'-hydroxycbamimidoyl]phenyl]phenyl]methyl]benzimidazole-4-cboxylate methyl 2-ethoxy-1-((2'-((hydroxyimino)(amino)methyl)biphenyl-4-yl)methyl)-1H-benzo[d]-imidazole-7-carboxylate methyl (Z)-2-ethoxy-1-((2'-(N'-hydroxyc bamimidoyl)-[1,1'-biphenyl]-4-yl)methyl)-1H-benzo[d]imidazole-7-cboxylate BEN730 2-Ethoxy-1-[[2'-[(hydroxyamino)iminomethyl][1,1'-biphenyl]-4-yl]methyl]-1H-benzimidazole-7-cboxylic acid methyl ester Methyl 2-Ethoxy-1-[[2'-(hydroxyamidino)biphenyl-4-yl]-1H-benzimidazole-7-cbo-xylate Methyl 2-Ethoxy-3-[2'-(N-hydroxycbamimidoyl)-biphenyl-4-ylmethyl]-3H-benzoimidazole-4-cboxylic acid Azilstan N-Hydroxy Methyl Ester Methyl2-ethoxy-1-[[2'-[(hydroxyamino)iminomethyl][1,1'-biphenyl]-4-yl]methyl]-1H-benzimidazole-7-cboxylate Azilstan Impurity 19 Methyl (Z)-2-ethoxy-1-((2'-(N'-hydroxycbamimidoyl)-[1,1'-biphenyl]-4-yl)methyl)-1H-indole-7-cboxylate Methyl(Z)-2-ethoxy-1-((2'-(N'-hydroxycbamimidoyl)-[1,1'-biphenyl]-4-yl)methyl)-1H-indole-7-cboxylate 2-Ethoxy-[[2’-(hydroxyamidino) biphenyl-4-yl)methyl]-1-H-benzimidazole-7cboxylate Methyl 2-ethoxy-1-((2'-(N-hydroxycbamimidoyl)-[1,1'-biphenyl]-4-yl)methyl)-1H-benzo[d]imidazole-7-cboxylate 1H-Benzimidazole-7-cboxylic acid, 2-ethoxy-1-[[2'-[(hydroxyamino)iminomethyl][1,1'-biphenyl]-4-yl]methyl]-, methyl ester Methyl 2-ethoxy-1-((2'-(N-hydroxycbamimidoyl)-[1,1'-biphenyl]-4-yl)methyl)-1H-benzo[d]imidaz Methyl 2-ethoxy-1-{[2'-(N-hydroxycarbamimidoyl)-[1,1'-biphenyl]-4-yl]methyl)]-1H-benzo[d]imidazole-7-carboxylate 2-Ethoxy-1-｛[2'-(N'-hydroxycbaMiMidoyl)biphenyl-4-yl]Methyl｝-1H-benzo[d]iMidazole-7 -cboxylic acid Methyl ester T56 BN DNJ B1R DR BYUM&MQ& CO2 IVO1 2-Ethoxy-1-[[2'-[(hydroxyamino)iminomethyl][1,1'-biphenyl]-4-yl]methyl]-1H-benzimidazole-7-carboxylic Acid Methyl Ester QC-8897 (Z)-Methyl2-ethoxy-3-((2'-(N'-hydroxycbaMiMidoyl)biphenyl-4-yl)Methyl)-3H-benzo[d]iMidazole-4-cboxylate Methyl 2-ethoxy-1-((2'-(N-hydroxycbamimidoyl)-[1,1'-biphenyl]-4-yl)methyl)-1H-benzo[d]imidazole 1'-biphenyl]-4-yl]methyl]-1H-benzimidazole-7-cboxylic Acid methyl ester 1-[(2'-(Hydroxyamidino)[1,1'-biphenyl]-4-yl)methyl]-2-ethoxy-1H-benzimidazole-7-cboxylicacidmethylester (Z)-Methyl 2-ethoxy-3-((2'-(N'-hydroxycbaMiMidoyl)biphenyl-4-yl)Methyl)-3H-benzo[d] iMidazole-4-ca Methyl 2-ethoxy-1-{[2'-(N-hydroxycarbamimidoyl)-4-biphenylyl]methyl}-1H-benzimidazole-7-carboxylate (Z)-methyl 2-ethoxy-1-((2'-(N'-hydroxycbamimidoyl)-[1,1'-biphenyl]-4-yl)methyl)-1H-benzo[d]imidazole-7-cboxylate Azilstan impurity T Azilstan Impurity 46 methyl 2-ethoxy-1-{[2'-(N-hydroxycarbamimidoyl)biphenyl-4-yl]methyl}-1H-benzimidazole-7-carboxylate Azilstan impurity 21/Methyl 2-ethoxy-1-((2'-(N-hydroxycbamimidoyl)-[1,1'-biphenyl]-4-yl)methyl)-1H-benzo[d]imidazole-7-cboxylate (Z)-methyl 2-ethoxy-1-((2'-(N'-hydroxycbamimidoyl) methyl 2-ethoxy-1-((2'-((hydroxyamino)iminomethyl)biphenyl-4-yl)methyl)-1H-benzo[d]-imidazole-7-carboxylate methyl 2-ethoxy-1-{[2'-(N-hydroxycbamimidoyl)biphenyl-4-yl]methyl}-1H-benzimidazole-7-cboxylate 1H-Benzimidazole-7-carboxylic acid,2-ethoxy-1-[[2'-[(hydroxyamino)iminomethyl][1,1'-biphenyl]-4-yl]methyl]-,methyl ester Methyl 2-Ethoxy-1-[[2’-(hydroxyamidino)biphenyl-4-yl]methyl]-1H-benzimidazole-7-cboxylate methyl (Z)-2-ethoxy-1-((2'-(N'-hydroxycbamimidoyl)-[1,1'-biphenyl]-4-yl)methyl)-1H-benzo[d]imidazole-7-cboxylate Azilstan intermediates 2-ethoxy-1-((2'-((hydroxyamino)iminomethyl)(1,1'-biphenyl)-4-yl)methyl)-1h-benzimidazole-7-carboxylic acid methyl ester Intermediate of Azilstan Medoxomil Methyl-2-Ethoxy-1-[[2'-Hydroxycbamimidoyl)Biphenyl)-4-yl]-Methyl-1H-Benzimidazole-7-Cboxylate 2-ethoxy-1-((2'-((hydroxyamino)iminomethyl)(1,1'-biphenyl)-4-yl)methyl)-1h-benzimidazole-7-cboxylic acid methyl ester Azilstan impurity07 (Z)-Methyl 2-ethoxy-3-((2'-(N'-hydroxycbaMiMidoyl)biphenyl-4-yl)Methyl)-3H-benzo[d] iMidazole-4-cboxylate 1H-Benzimidazole-7-carboxylic acid, 2-ethoxy-1-[[2'-[(hydroxyamino)iminomethyl][1,1'-biphenyl]-4-yl]methyl]-, methyl ester (Z)-Methyl 2-ethoxy-1-((2'-(N'-hydroxycbaMiMidoyl)biphenyl-4-yl)Methyl)-1H-benzo[d]iMidazole-7-cboxylate Azilstan-20 InterMediate of Azilstan 2-Ethoxy-1-[[2a€-[(hydroxyamino)iminomethyl][1,1a€-biphenyl]-4-yl]methyl]-1H-benzimidazole-7-cboxylic Acid Methyl Ester 2-Ethoxy-1-[[2′-[(hydroxyamino)iminomethyl][1,1′-biphenyl]-4-yl]methyl]-1H-benzimidazole-7-cboxylic Acid Methyl Ester 2-Ethoxy-1-[[2'-[(hydroxyamino)iminomethyl][1,1'-biphenyl]-4-yl]methyl]-1H-benzimidazole

Density	1.3±0.1 g/cm3
Boiling Point	657.2±65.0 °C at 760 mmHg
Melting Point	207-209°C
Molecular Formula	C₂₅H₂₄N₄O₄
Molecular Weight	444.483
Flash Point	351.2±34.3 °C
Exact Mass	444.179749
PSA	109.46000
LogP	4.33
Vapour Pressure	0.0±2.1 mmHg at 25°C
Index of Refraction	1.640

Hazard Codes	Xi

139481-44-0

~85%

147403-65-4

Literature: RANBAXY LABORATORIES LIMITED; AZAD, Md Abul Kalam; KSHIRSAGAR, Prakash Bhimaji; SINGH, Shravan, Kumar; TIWARI, Anand, Prakash; SINGH, Kaptan; PRASAD, Mohan; ARORA, Sudershan, Kumar Patent: WO2013/114305 A1, 2013 ; Location in patent: Page/Page column 15; 16 ;

1403477-45-1

~7%

147403-65-4

147403-03-0

Literature: WO2012/139535 A1, ; Page/Page column 12-13 ;

139481-44-0

139481-33-7

147403-65-4

Literature: WO2012/119573 A1, ; Page/Page column 12-13 ;

Precursor 1
139481-44-0
DownStream 4
863031-21-4 147403-03-0 147403-52-9 108-95-2

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