Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 4-Aminobutyric acid
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: γ-aminobutyric acid
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson
Email: info@tianfuchem.com

56-12-2

56-12-2 structure

Name: 4-Aminobutanoic acid
Chemical Name: γ-aminobutyric acid
CAS Number: 56-12-2
Molecular Formula: C₄H₉NO₂
Molecular Weight: 103.120
Catalog: API Digestive system medication Antiemetic emetic
Create Date: 2018-07-14 16:11:26
Modify Date: 2026-07-01 10:41:49
γ-Aminobutyric acid (4-Aminobutyric acid) is a major inhibitory neurotransmitter in the adult mammalian brain[1][2], binding to the ionotropic GABA receptors (GABAA receptors) and metabotropic receptors (GABAB receptors)[2].

Name	γ-aminobutyric acid
Synonyms	df468 gamma-Aminobuttersaeure MFCD00008226 AURORA KA-1053 ALPHA-AMINOBUTANOIC ACID H-GAMMA-ABU-OH RECHEM EM WB 0019 Immuglobin GAMMA-AMINOBUTYRIC ACID H-4-AMINOBUTYRIC ACID 4-Aminobutyric acid;4-Aminobutanoic acid; GABA AMINOBUTYRIC-4 ACID gamma-Aminobutanoic acid gamma-aminobutyric acid PIPERIDIC ACID Gamex omega-Aminobutyric acid NH2-(CH2)3-COOH PhMagaba 20 PhMagaba Gamulin GABA Gammalon γ-Amino-n-butyric acid Gamm 4-AMINOBUTYRIC ACID 4-AMINO-N-BUTYRIC ACID Gammagee Reanal Globulin, immune human serum PhMa-GABA 20S g-Amino-n-butyric Acid Oryza GABA Extract HC 90 aminobutyric gamma-Aminobutryic acid H-ABU(GAMMA)-OH Mielogen γ-Aminobutyric acid,4-Aminobutanoic acid, GABA, Piperidic acid, Piperidinic acid AMINOBUTYRIC ACID, gamma-(GABA)(P) H-GABA-OH H-ABU(4)-OH 4-Aminobutyric acid, synthesis ade Gammalone Gamastan Mielomade PhMagaba 20D AMINOBUTYRIC ACID, 4 Immu-G g-Aminobutyric acid DL-GAMMA-AMINO-N-BUTYRIC ACID Gaballon EINECS 200-258-6 Gammasol GAMMA-AMINO-N-BUTYRIC ACID 4-AMinobutanoic Αcid 4-AMINOBUTANOIC ACID PIPERIDINIC ACID 4-Aminobutyric acid gamma

Description	γ-Aminobutyric acid (4-Aminobutyric acid) is a major inhibitory neurotransmitter in the adult mammalian brain[1][2], binding to the ionotropic GABA receptors (GABAA receptors) and metabotropic receptors (GABAB receptors)[2].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> GABA Receptor Signaling Pathways >> Neuronal Signaling >> GABA Receptor Natural Products >> Others Research Areas >> Neurological Disease
Target	GABA Receptor[1][2]
References	[1]. Watanabe M, et al. GABA and GABA receptors in the central nervous system and other organs. Int Rev Cytol. 2002;213:1-47. [2]. Okada R, et al. Gamma-aminobutyric acid (GABA)-mediated neural connections in the Drosophila antennal lobe. J Comp Neurol. 2009 May 1;514(1):74-91. [3]. Chen S, et al. Effects of dietary gamma-aminobutyric acid supplementation on the intestinal functions in weaning piglets. Food Funct. 2019 Jan 2.

Density	1.1±0.1 g/cm3
Boiling Point	248.0±23.0 °C at 760 mmHg
Melting Point	195-204ºC
Molecular Formula	C₄H₉NO₂
Molecular Weight	103.120
Flash Point	103.8±22.6 °C
Exact Mass	103.063332
PSA	63.32000
LogP	-0.64
Vapour Pressure	0.0±1.0 mmHg at 25°C
Index of Refraction	1.465
Storage condition	Store at RT.
Water Solubility	H2O: 1 M at 20 °C, clear, colorless \| SOLUBLE

CHEMICAL IDENTIFICATION

RTECS NUMBER :: ES6300000

CHEMICAL NAME :: Butyric acid, 4-amino-

CAS REGISTRY NUMBER :: 56-12-2

LAST UPDATED :: 199701

DATA ITEMS CITED :: 11

MOLECULAR FORMULA :: C4-H9-N-O2

MOLECULAR WEIGHT :: 103.14

WISWESSER LINE NOTATION :: Z3VQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 5400 mg/kg

TOXIC EFFECTS :: Behavioral - general anesthetic Behavioral - altered sleep time (including change in righting reflex) Lungs, Thorax, or Respiration - other changes

REFERENCE :: AITEAT Archivum Immunologiae et Therapiae Experimentalis. (Ars Polona, POB 1001, 00-068 Warsaw 1, Poland) V.10- 1962- Volume(issue)/page/year: 13,70,1965

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intracerebral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 18 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 14,1901,1965

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 12680 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 85,463,1965

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 4950 mg/kg

TOXIC EFFECTS :: Behavioral - general anesthetic Behavioral - altered sleep time (including change in righting reflex) Lungs, Thorax, or Respiration - other changes

REFERENCE :: AITEAT Archivum Immunologiae et Therapiae Experimentalis. (Ars Polona, POB 1001, 00-068 Warsaw 1, Poland) V.10- 1962- Volume(issue)/page/year: 13,70,1965

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 9210 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 85,463,1965

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2748 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 145,233,1963

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 7230 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BTMNA7 Bitamin. (Nippon Bitamin Gakkai, 4 Ushinomiya-cho, Yoshida, Sakyo-Ku, Kyoto 606, Japan) V.1- 1948- Volume(issue)/page/year: 25,297,1962

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - cat

DOSE/DURATION :: 5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 47,205,1984

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 2400 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AITEAT Archivum Immunologiae et Therapiae Experimentalis. (Ars Polona, POB 1001, 00-068 Warsaw 1, Poland) V.10- 1962- Volume(issue)/page/year: 13,70,1965 *** REVIEWS *** TOXICOLOGY REVIEW AITEAT Archivum Immunologiae et Therapiae Experimentalis. (Ars Polona, POB 1001, 00-068 Warsaw 1, Poland) V.10- 1962- Volume(issue)/page/year: 13,70,1965

Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi:Irritant
Risk Phrases	R36/37/38
Safety Phrases	S26-S36
RIDADR	NONH for all modes of transport
WGK Germany	2
RTECS	ES6300000
HS Code	29224995

Precursor 9
100340-10-1 21994-40-1 56-86-0 692-29-5
57294-38-9 16051-87-9 13325-10-5 616-45-5
10137-67-4
DownStream 10
107466-55-7 10466-75-8 5105-78-2 3130-75-4
50632-83-2 57078-98-5 57294-38-9 141985-40-2
463-00-3 13477-53-7

HS Code	2922499990
Summary	HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

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