Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: 5-Hydroxytryptophan
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DC Chemicals Limited
China
Product Name: 5-Hydroxytryptophan
Price: $280.0/20mg
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Nanjing Peptide Biotech Ltd
China
Product Name: H-L-Trp(5-OH)-OH
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Zhejiang Hangyu API Co., Ltd
China
Product Name: 5-Hydroxytryptophan
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Henan Tianfu Chemical Co., Ltd.
China
Product Name: DL-5-Hydroxytryptophan
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56-69-9

56-69-9 structure

56-69-9 structure

Name: 5-Hydroxytryptophan
Chemical Name: DL-5-Hydroxytryptophan
CAS Number: 56-69-9
Molecular Formula: C₁₁H₁₂N₂O₃
Molecular Weight: 220.225
Catalog: Inorganic chemical industry Inorganic salt Metal sulfides and sulfates
Create Date: 2018-03-27 08:00:00
Modify Date: 2024-01-01 17:36:04
5-Hydroxytryptophan, a tryptophan metabolite, is a direct 5-hydroxytryptamine (5-HT) precursor and an L-aromatic amino acid decarboxylase substrate. [1][2][3].

Name	DL-5-Hydroxytryptophan
Synonyms	MFCD00005651 5-HYDROXY-TRYPTOPHAN Tryptophan, 5-hydroxy-, DL- 5-Hydroxytryptophan DL-form DL-5-HTP 2-Chloro-3-methylamine-5-trifluoromethylpyridine hydrochloride Tryptophan, 5-hydroxy- EINECS 200-284-8 (±)-5-hydroxytryptophan 5-Hydroxytryptophan 5-Hydroxy Tryptophan Dl-5-Hydroxytryptophan

Description	5-Hydroxytryptophan, a tryptophan metabolite, is a direct 5-hydroxytryptamine (5-HT) precursor and an L-aromatic amino acid decarboxylase substrate. [1][2][3].
Related Catalog	Research Areas >> Metabolic Disease
Target	Human Endogenous Metabolite
References	[1]. Gartside SE, et al. Mediation of ACTH and prolactin responses to 5-HTP by 5-HT2 receptors. Eur J Pharmacol. 1990 Apr 10;179(1-2):103-9. [2]. Gijsman HJ, et al. Placebo-controlled comparison of three dose-regimens of 5-hydroxytryptophan challenge test in healthy volunteers. J Clin Psychopharmacol. 2002 Apr;22(2):183-9. [3]. Schruers K, et al. Acute L-5-hydroxytryptophan administration inhibits carbon dioxide-induced panic in panic disorder patients. Psychiatry Res. 2002 Dec 30;113(3):237-43.

Density	1.5±0.1 g/cm3
Boiling Point	520.6±50.0 °C at 760 mmHg
Melting Point	298-300ºC
Molecular Formula	C₁₁H₁₂N₂O₃
Molecular Weight	220.225
Flash Point	268.7±30.1 °C
Exact Mass	220.084793
PSA	99.34000
LogP	-0.14
Vapour Pressure	0.0±1.4 mmHg at 25°C
Index of Refraction	1.737
Storage condition	2-8°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: YN7000000

CHEMICAL NAME :: Tryptophan, 5-hydroxy-

CAS REGISTRY NUMBER :: 56-69-9

LAST UPDATED :: 199701

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C11-H12-N2-O3

MOLECULAR WEIGHT :: 220.25

WISWESSER LINE NOTATION :: T56 BMJ D1YZVQ GQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD277-689 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

DOSE :: 30 mg/kg

SEX/DURATION :: male 1 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Fertility - mating performance (e.g. # sperm positive females per # females mated; # copulations per # estrus cycles)

REFERENCE :: ANENAG Annales d'Endocrinologie. (Masson Editeur, 120 Blvd. Saint-Germain, F-25280 Paris Cedex 06, France) V.1- 1939- Volume(issue)/page/year: 24(Suppl 3),1,1963 *** REVIEWS *** TOXICOLOGY REVIEW CLPTAT Clinical Pharmacology and Therapeutics (St. Louis). (C.V. Mosby Co., 11830 Westline Industrial Dr., St. Louis, MO 63146) V.1- 1960- Volume(issue)/page/year: 5,480,1964

Hazard Codes	Xn
Risk Phrases	22-36/37/38-65-20/21/22-20/21
Safety Phrases	24/25-22
RIDADR	UN 2811
WGK Germany	3.0
RTECS	YN7100000
Packaging Group	III
HS Code	2929909090

100-22-1 structure

100-22-1

126216-42-0 structure

126216-42-0

~%

100-22-1 structure

100-22-1

56-69-9 structure

56-69-9

Literature: Journal of Physical Chemistry, , vol. 86, p. 3661 - 3667

619-60-3 structure

619-60-3

126216-42-0 structure

126216-42-0

~%

54737-34-7 structure

54737-34-7

56-69-9 structure

56-69-9

Literature: Journal of Physical Chemistry, , vol. 86, p. 3661 - 3667

126216-42-0 structure

126216-42-0

150-76-5 structure

150-76-5

~%

6119-32-0 structure

6119-32-0

56-69-9 structure

56-69-9

Literature: Journal of Physical Chemistry, , vol. 86, p. 3661 - 3667

126216-42-0 structure

126216-42-0

108-46-3 structure

108-46-3

~%

24856-47-1 structure

24856-47-1

56-69-9 structure

56-69-9

Literature: Journal of Physical Chemistry, , vol. 86, p. 3661 - 3667

Precursor 4
100-22-1 619-60-3 150-76-5 108-46-3
DownStream 5
50-67-9 150-76-5 108-46-3 100-22-1
619-60-3

HS Code	2929909090
Summary	2929909090 other compounds with other nitrogen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%