| Name | Ethyl N-(4-methylphenyl)sulfonylcarbamate |
|---|---|
| Synonyms |
Tosylcarbamic acid ethyl ester
Ethyl [(4-methylphenyl)sulfonyl]carbamate ethyl N-(4-toluenesulfonyl)carbamate ethyl tosylcarbaMate Ethyl [(4-methylphenyl)sulphonyl]carbamate Carbamic acid, N-[(4-methylphenyl)sulfonyl]-, ethyl ester Tosylurethane ethoxycarbonamide of p-toluenebenzenesulfoacid ethyl p-tosylcarbamate (toluene-4-sulfonyl)-carbamic acid ethyl ester ethyl N-(tosyl)carbamate Carbamic acid, [(4-methylphenyl)sulfonyl]-, ethyl ester N-(4-methylphenyl)sulfonylcarbamic acid ethyl ester 2OVMSWR D1 N-(p-Tolylsulfonyl)carbamic acid ethyl ester |
| Description | Ethyl tosylcarbamate is an intermediate in the synthesis of Gliclazide (G409877)[1][2]. Gliclazide is a whole-cell beta-cell ATP-sensitive potassium currents blocker with an IC50 of 184 nM[3]. |
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| Related Catalog | |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Molecular Formula | C10H13NO4S |
| Molecular Weight | 243.279 |
| Exact Mass | 243.056534 |
| PSA | 80.85000 |
| LogP | 1.86 |
| Index of Refraction | 1.530 |
| Hazard Codes | Xi |
|---|---|
| HS Code | 2935009090 |
|
~88%
5577-13-9 |
| Literature: Xi, Pin-xian; Xu, Zhi-hong; Liu, Xiao-hui; Cheng, Feng-juan; Zeng, Zheng-zhi Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy, 2008 , vol. 71, # 2 p. 523 - 528 Title/Abstract Full Text View citing articles Show Details Xi, Pin-Xian; Xu, Zhi-Hong; Liu, Xiao-Hui; Chen, Feng-Juan; Huang, Liang; Zeng, Zheng-Zhi Chemical and Pharmaceutical Bulletin, 2008 , vol. 56, # 4 p. 541 - 546 |
|
~%
5577-13-9 |
| Literature: US5326796 A1, ; |
|
~91%
5577-13-9 |
| Literature: Guo, Xiaoguang; Shang, Jianpeng; Li, Jian; Wang, Liguo; Ma, Yubo; Shi, Feng; Deng, Youquan Synthetic Communications, 2011 , vol. 41, # 8 p. 1102 - 1111 |
|
~33%
5577-13-9 |
| Literature: Bittner, Shmuel; Assaf, Yonit; Krief, Penina; Pomerantz, Martin; Ziemnicka, Barbara T.; Smith, Christina G. Journal of Organic Chemistry, 1985 , vol. 50, # 10 p. 1712 - 1718 |
|
~%
5577-13-9 |
| Literature: J. Gen. Chem. USSR (Engl. Transl.), , vol. 31, p. 2381 - 2385,2218 - 2222 |
|
~%
5577-13-9 |
| Literature: J. Gen. Chem. USSR (Engl. Transl.), , vol. 31, p. 2381 - 2385,2218 - 2222 |
| Precursor 7 | |
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| DownStream 7 | |
| HS Code | 2935009090 |
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| Summary | 2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0% |