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108-53-2

108-53-2 structure
108-53-2 structure
  • Name: Isocytosine
  • Chemical Name: 2-amino-4-hydroxypyrimidine
  • CAS Number: 108-53-2
  • Molecular Formula: C4H5N3O
  • Molecular Weight: 111.102
  • Catalog: Biochemical Nucleoside drugs Nucleotides and their analogues
  • Create Date: 2018-08-14 10:55:11
  • Modify Date: 2024-01-03 15:20:07
  • Isocytosine is a non-natural nucleobase and an isomer of cytosine. It is used in combination with Isoguanine in studies of unnatural nucleic acid analogues of the normal base pairs in DNA and used as a nucleobase of hachimoji RNA[1][2].

Name 2-amino-4-hydroxypyrimidine
Synonyms 4(1H)-Pyrimidinone, 2-amino- (9CI)
2-amino-4-oxo-3,4-dihydropyrimidine
4(3H)-pyrimidinone, 2-amino-
2-amino-3H-pyrimidin-4-one
Isocytosine
2-Amino-4-pyrimidone
2-Aminopyrimidin-4-ol
2-amino-4-hydroxypyrimine
2-Amino-4-hydroxypyrimidine
4-Hydroxy-2-aminopyrimidine
2-amino-1H-pyrimidin-6-one
MFCD00057557
2-Amino-4-hydroxypyrimidine,2-Aminouracil
2-Aminopyrimidin-4(1H)-one
Iso Cytosine
2-Amino-4(1H)-pyrimidinone
2-Aminopyrimidin-4(3H)-one
2-Amino-6-hydroxpyrimidine
EINECS 203-592-0
2-aminouracil
4-Pyrimidinol, 2-amino-
Description Isocytosine is a non-natural nucleobase and an isomer of cytosine. It is used in combination with Isoguanine in studies of unnatural nucleic acid analogues of the normal base pairs in DNA and used as a nucleobase of hachimoji RNA[1][2].
Related Catalog
References

[1]. "Isocytosine". Molecule of the Week. American Chemical Society. Retrieved November 1, 2012.

[2]. Hoshika S, et al. Hachimoji DNA and RNA: A genetic system with eight building blocks. Science. 2019 Feb 22;363(6429):884-887.

Density 1.5±0.1 g/cm3
Boiling Point 393.6±34.0 °C at 760 mmHg
Melting Point 275°C
Molecular Formula C4H5N3O
Molecular Weight 111.102
Flash Point 191.9±25.7 °C
Exact Mass 111.043259
PSA 72.03000
LogP -1.01
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.668
Storage condition Room temperature.
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302-H319
Precautionary Statements P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn:Harmful;
Risk Phrases R22;R36
Safety Phrases S26
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2933599090
HS Code 2933599090
Summary 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%