BioBioPha
China
Product Name: Pinoresinol
Price: ￥Inquiry/10mg
Purity: 98.0%
Stocking Period: 1 Day
Contact: Xueping-Zheng

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Pinoresinol
Price: ￥1920.0/5mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: (+)-Pinoresinol
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Phenol,4,4'-[(1S,3aR,4S,6aR)-tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl]bis[2-methoxy-
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

487-36-5

487-36-5 structure

487-36-5 structure

Name: Pinoresinol
Chemical Name: (+)-pinoresinol
CAS Number: 487-36-5
Molecular Formula: C₂₀H₂₂O₆
Molecular Weight: 358.385
Catalog: Natural product Lignans
Create Date: 2018-06-24 01:37:10
Modify Date: 2024-01-01 18:10:04
Pinoresinol is a lignol of plant origin serving for defense in a caterpillar. Pinoresinol drastically sensitizes cancer cells against TNF-related apoptosis-inducing ligand (TRAIL) -induced apoptosis[1][2].

Name	(+)-pinoresinol
Synonyms	(+)-PINORESINOL 4,4'-(1S,3aR,4S,6aR)-Tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diylbis(2-methoxyphenol) Phenol, 4,4'-[(1S,3aR,4S,6aR)-tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl]bis[2-methoxy- Pinoresinol

Description	Pinoresinol is a lignol of plant origin serving for defense in a caterpillar. Pinoresinol drastically sensitizes cancer cells against TNF-related apoptosis-inducing ligand (TRAIL) -induced apoptosis[1][2].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer
In Vitro	Pinoresinol facilitated death-inducing signaling complex formation to trigger a caspase-8-dependent apoptotic cascade activation in TRAIL-resistant glioblastoma cells[2].
References	[1]. Schroeder FC, et al. Pinoresinol: A lignol of plant origin serving for defense in a caterpillar. Proc Natl Acad Sci U S A. 2006 Oct 17;103(42):15497-501. [2]. Lee SR, et al. Accelerated degradation of cFLIPL and sensitization of the TRAIL DISC-mediated apoptotic cascade by pinoresinol, a lignan isolated from Rubia philippinensis. Sci Rep. 2019 Sep 18;9(1):13505.

Density	1.3±0.1 g/cm3
Boiling Point	556.5±50.0 °C at 760 mmHg
Melting Point	121 °C
Molecular Formula	C₂₀H₂₂O₆
Molecular Weight	358.385
Flash Point	290.4±30.1 °C
Exact Mass	358.141632
PSA	77.38000
LogP	1.54
Appearance	white to tan
Vapour Pressure	0.0±1.6 mmHg at 25°C
Index of Refraction	1.598
Storage condition	?20°C
Water Solubility	DMSO: ≥6mg/mL

Hazard Codes	Xi
RIDADR	NONH for all modes of transport