56-57-5

56-57-5 structure

Name: 4-Nitroquinoline 1-oxide
Chemical Name: 4-nitroquinoline N-oxide
CAS Number: 56-57-5
Molecular Formula: C₉H₆N₂O₃
Molecular Weight: 190.16
Catalog: Pharmaceutical intermediate Heterocyclic compound Pyridine compound Chloropyridine
Create Date: 2018-06-15 09:41:55
Modify Date: 2026-07-16 15:20:21
Nitrochin (4-NQO) is a chemical carcinogen. Nitrochin induces oncostatin-M (OSM) in esophageal cells. Nitrochin induces DNA damage, and induces apoptosis via a p53-dependent mitochondrial signaling pathway[1][2].

Name	4-nitroquinoline N-oxide
Synonyms	4-NITROQUINOLINE 1-OXIDE 4-nqo 4-NITROCHINOLINE-N-OXIDE NITROQUINOLINE-N-OXIDE 4-NITROQUINOLINE N-OXIDE MFCD00006738 nitrochin 4-Nitroquinoline-1-oxide@100 μg/mL in Dichloromethane 4-NitroquinolineN-Oxide> 4-NITRO-1-QUINOLINIUMOLATE 4-nitroquinoline n-oxide 4-nitroquinolineoxide 4-Nitroquinoline-N-oxide Solution in Methanol 4-NITROQUINOLINE N-OXIDE POWDER Quinoline, 4-nitro-, 1-oxide 4-nitro-quinolin1-oxide EINECS 200-281-1 4-Nitroquinoline-N-oxide, HPLC 4-nitro-1-oxido-quinolin-1-ium 4-NQNO 4-nitro-1-oxidoquinolin-1-ium 4-nitrochinolinn-oxid 4-Nitroquinoline 1-oxide, 10 mM in DMSO 4-nitroquinoline-N-oxide Cyclohexane Impurity 26 4-nitrochinolinn-oxid(swedish) 4-Nitroquinoline-N-oxide, Comet assay ade N-NITROQUINOLINE-N-OXIDE, 1000MG, NEAT 4 Nitroquinoline 1 oxide,4Nitroquinoline 1oxide 4-NDQ Sigma N8141 4-NQO NITROQUINOLINE-1-OXIDE 4-NITROQUINOLINIUM-1-OLATE N-(4-Nitrobenz Nitroquinolineoxide TIMTEC-BB SBB006266 4-NITROQUINOLINE N-OXIDE ISO 9001：2015 REACH

Description	Nitrochin (4-NQO) is a chemical carcinogen. Nitrochin induces oncostatin-M (OSM) in esophageal cells. Nitrochin induces DNA damage, and induces apoptosis via a p53-dependent mitochondrial signaling pathway[1][2].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer
References	[1]. Mukherjee A, et al. Carcinogen 4-Nitroquinoline Oxide (4-NQO) Induces Oncostatin-M (OSM) in Esophageal Cells. In Vivo. 2023 Mar-Apr;37(2):506-518. [2]. Han H, et al. 4-NQO induces apoptosis via p53-dependent mitochondrial signaling pathway. Toxicology. 2007 Feb 12;230(2-3):151-63.

Density	1.4±0.1 g/cm3
Boiling Point	387.6±34.0 °C at 760 mmHg
Melting Point	154-156 °C(lit.)
Molecular Formula	C₉H₆N₂O₃
Molecular Weight	190.16
Flash Point	188.2±25.7 °C
Exact Mass	190.037842
PSA	71.28000
LogP	0.92
Vapour Pressure	0.0±0.9 mmHg at 25°C
Index of Refraction	1.659
Storage condition	−20°C
Stability	Stable. Hygroscopic, light-sensitive. Incompatible with strong oxidizing agents.
Water Solubility	acetone: clear to hazy

Symbol	GHS08
Signal Word	Danger
Hazard Statements	H350
Precautionary Statements	P201-P308 + P313
Personal Protective Equipment	Eyeshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes	Xn:Harmful;
Risk Phrases	R33
Safety Phrases	S53-S45
RIDADR	2811
WGK Germany	3
RTECS	VC2100000
Packaging Group	II
Hazard Class	6.1