7423-55-4
7423-55-4 structure
- Name: 3-Maleimidopropionic acid
- Chemical Name: 3-Maleimidopropionic Acid
- CAS Number: 7423-55-4
- Molecular Formula: C7H7NO4
- Molecular Weight: 169.135
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-06-30 16:30:23
- Modify Date: 2026-07-08 16:21:01
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3-Maleimidopropionic acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | 3-Maleimidopropionic Acid |
|---|---|
| Synonyms |
MPS-Acid (QBD-10323)
N-(2-Cboxyethyl)maleimide, 3-Maleimidopropionic acid [MAL-PA] 3-Maleimide propionic acid 3-MaleiMidopropioniccid (BMPA) 3-Maleimidopropionic acid(MPA) 3-(2,5-DIOXO-2,5-DIHYDRO-1H-PYRROL-1-YL)PROPANOIC ACID 1H-Pyrrole-1-propanoic acid, 2,5-dihydro-2,5-dioxo 3-(2,5-Dioxopyrrol-1-yl)propanoic acid N-Maleoyl-β-ananine β-Maleimidopropionic acid 3-Maleinimidopropionicacid BETA-MALEIMIDOPROPIONIC ACID 3-(2,5-dioxopyrrol-1-yl)propanoic acid N-BETA-MALEIMIDOPROPIONIC ACID 2,5-Dihydro-2,5-dioxo-1H-pyrrole-1-propanoic Acid B-MALEIMIDOPROPIONIC ACID 3-(2,5-Dioxo-2,5-dihydro-pyrrol-1-yl)-prop Mal-(CH2)2-COOH (MPA) 3-MaleimidopropionicAcid> MPA-OH Maleimide-(CH2)2-COOH BMPA 3-(2,5-Dioxo-2,5-dihydropyrrol-1-yl)propanoic acid 3-MALEIMIDOPROPIONIC ACID MFCD00043030 N-Maleoyl-β-alanine N-Maleoyl-β-alanine,3-Maleimidopropionic acid, N-(2-Cboxyethyl)maleimide 3-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)propa 3-Maleimidopropionicacid RECHEM AL CD 0912 3-Maleimidopropionic acid, N-(2-Cboxyethyl)maleimide 3-Maleimidopropionic Mal-(CH2)2-COOH N-MALEOYL-BETA-ALANINE MPA 3-Maleimidopropionic acid 3-maleimide propionic acid Maleoyl-bAla-OH, MPA-OH, 3-(2,5-Dioxo-2,5-dihydro-pyrrol-1-yl)-propionic acid 3-Maleimidopropionic acid dihydrate 3-(2,5-DIOXO-2,5-DIHYDRO-PYRROL-1-YL)-PROPIONIC ACID N-(2-CBOXYETHYL)MALEIMIDE MALEOYL-BETA-ALA-OH 3-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanoic acid 3-maleimidopropropionic acid 3-MALEIMIDOPROPIONOIC ACID DIHYDRATE |
| Description | 3-Maleimidopropionic acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
Alkyl-Chain |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 382.5±25.0 °C at 760 mmHg |
| Melting Point | 103-106 °C(lit.) |
| Molecular Formula | C7H7NO4 |
| Molecular Weight | 169.135 |
| Flash Point | 185.1±23.2 °C |
| Exact Mass | 169.037506 |
| PSA | 74.68000 |
| LogP | 0.04 |
| Vapour Pressure | 0.0±1.9 mmHg at 25°C |
| Index of Refraction | 1.565 |
| Storage condition | -15°C |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi: Irritant; |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2925190090 |
| Precursor 4 | |
|---|---|
| DownStream 4 | |
| HS Code | 2925190090 |
|---|---|
| Summary | 2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |