Name | β-alanine |
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Synonyms |
3-Aminopropanoic acid
beta-alanine 3-Aminopropionic Acid EINECS 203-536-5 MFCD00008200 β-Alanine H-β-Ala-OH |
Description | β-Alanine is a non-essential amino acid that is shown to be metabolized into carnosine, which functions as an intracellular buffer. |
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Related Catalog | |
Target |
Human Endogenous Metabolite |
In Vitro | Cells treated with β-alanine display significantly suppressed basal and peak ECAR (aerobic glycolysis), with simultaneous increase in glucose transporter 1 (GLUT1). Additionally, cells treated with β-alanine exhibit significantly reduced basal and peak OCR (oxidative metabolism), which is accompanied by reduction in mitochondrial content with subsequent suppression of genes which promote mitochondrial biosynthesis. Suppression of glycolytic and oxidative metabolism by β-alanine results in the reduction of total metabolic rate, although cell viability is not affected.β-alanine is shown to reduce both cell migration and proliferation without acting in a cytotoxic fashion. Moreover, β-alanine significantly increases malignant cell sensitivity to doxorubicin, suggesting a potential role as a co-therapeutic agent[1]. |
References |
Density | 1.2±0.1 g/cm3 |
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Boiling Point | 237.1±23.0 °C at 760 mmHg |
Melting Point | 202 °C (dec.)(lit.) |
Molecular Formula | C3H7NO2 |
Molecular Weight | 89.093 |
Flash Point | 97.2±22.6 °C |
Exact Mass | 89.047676 |
PSA | 63.32000 |
LogP | -0.86 |
Vapour Pressure | 0.0±1.0 mmHg at 25°C |
Index of Refraction | 1.463 |
Storage condition | Store at RT. |
Water Solubility | H2O: 1 M at 20 °C, clear, colorless |
Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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Hazard Codes | Xi |
Risk Phrases | R36/37/38 |
Safety Phrases | S24/25 |
RIDADR | NONH for all modes of transport |
WGK Germany | 3 |
RTECS | UA2369200 |
HS Code | 29224920 |
Precursor 8 | |
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DownStream 10 | |
HS Code | 2922499990 |
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Summary | HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0% |