Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 9,12-Octadecadienoicacid (9Z,12Z)-, methyl ester
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Purity: 98.0%
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112-63-0

112-63-0 structure

Name: Methyl linoleate
Chemical Name: methyl linoleate
CAS Number: 112-63-0
Molecular Formula: C₁₉H₃₄O₂
Molecular Weight: 294.472
Catalog: Chemical reagent Organic reagent Ester Methyl ester compound
Create Date: 2018-08-29 17:36:34
Modify Date: 2026-07-07 08:45:24
Methyl linoleate, a major active constituent of Sageretia thea fruit (HFSF), is a major anti-melanogenic compound. Methyl linoleate downregulates microphthalmia-associated transcription factor (MITF) and tyrosinase-related proteins[1].

Name	methyl linoleate
Synonyms	LINOLEIC ACID METHYL ESTER extrapure 9,12-Octadecadienoic acid (Z,Z)-, methyl ester Methyl Linoleate [Standd Material] 9,12-Octadecadienoic acid (9Z,12Z)-, methyl ester Methyl cis-9,cis-12 linoleate METHYL LINOLEATE, STANDD FOR Methyl linoleate Solution, 100ppm methyl linolate Linoleic acid methyl ester, Methyl cis,cis-9,12-octadecadienoate Methyl lineoleate 9,12-Octadecadienoicacid(Z,Z)-,methylester C18:2 (CIS,CIS-9,12) METHYL ESTER Methyl (Z,Z)-9,12-octadecadienoate MethylLinoleate> Methyl 9-cis,12-cis-octadecadienoate Methyl Linoleate(C18:2) EINECS 203-993-0 METHYL LINOLEATE Linoleic acid, methyl ester (8CI) Linoleic acid methyl ester~Methyl cis,cis-octadeca-9,12-dienoate MethylLinoleate(9c,12c) METHYLLINOLEATE&METHYLLINOLENATEMIXTURE MethylLinoleate[StanddMaterialfor> Methyl Linoleate (5 x 50 mg)G0D1070.99mg/mg(ai) DELTA 9 CIS 12 OCTADECADIENOIC ACID METHYL ESTER Methyl Linoleate (5 x 50 mg) Methyl(Z,Z)-9,12-octadecadienate 12-octadecadienoicacid(z,z)-methylester 9,12-Octadecadienoic acid, methyl ester, (Z,Z) Methyl cis,cis-9,12-octadecadienoate cis-9,cis-12-octadecadienoic acid methyl ester Methyl linoleate (C18:2n6c) METHYLLINOLENAT METHYL CIS, CIS-9, 12-OCTADECADIENOATE methyllinolate Methyl linoleate (LA-ME) Methyl octadec-9,12-dienoate LINOLEIC ACID METHYL ESTER ADE II-S (9Z,12Z)-Octadeca-9,12-dienoic acid methyl ester METHYLLINOLEICACID (9Z,12Z)-9,12-Octadecadienoic acid methyl cis,cis-octadeca-9,12-dienoicacidmethylester Methylcis,cis-octadeca-9,12-dienoate MFCD00009534 methyl (Z,Z)-9,12-octadienoate Methyl linoleate @10.0 mg/mL in Htane (Z,Z)-9,12-octadecadienoic acid methyl ester Methyl linoleate (C18:2n6c) Solution Methyl (9Z,12Z)-9,12-octadecadienoate (9Z,12Z)-9,12-Octadecadienoic acid methyl ester METHYL LINOLEATE, NATURAL Methyl linoleate,Linoleic acid methyl ester, Methyl cis,cis-9,12-octadecadienoate Linoleic acid methyl ester Methyl Linoleate [Standd Material for Methyl (9Z,12Z)-octadeca-9,12-dienoate Methyl cis-9,cis-12-octadecadienoate Methyl octadecadienoate (9Z,12Z)-Methyl octadeca-9,12-dienoate LINOLEIC ACID METHYL ESTER Methyl cis,cis-octadeca-9,12-dienoate Radia CIS,CIS-9,12-OCTADECADIENOIC ACID METHYL ESTER 9,12-Methyl octadecadienoate

Description	Methyl linoleate, a major active constituent of Sageretia thea fruit (HFSF), is a major anti-melanogenic compound. Methyl linoleate downregulates microphthalmia-associated transcription factor (MITF) and tyrosinase-related proteins[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
In Vitro	Sageretia thea fruit extracts rich in Methyl linoleate downregulate melanogenesis via the Akt/GSK3β signaling pathway. The HFSF and Methyl linoleate inhibit β-catenin-mediated transcriptional activation of MITF through the Akt/GSK3β signaling pathway[1].
References	[1]. Ko GA, et al. Sageretia thea fruit extracts rich in methyl linoleate and methyl linolenate downregulate melanogenesis via the Akt/GSK3β signaling pathway. Nutr Res Pract. 2018 Feb;12(1):3-12.

Density	0.9±0.1 g/cm3
Boiling Point	373.3±21.0 °C at 760 mmHg
Melting Point	-35ºC(lit.)
Molecular Formula	C₁₉H₃₄O₂
Molecular Weight	294.472
Flash Point	96.9±20.4 °C
Exact Mass	294.255890
PSA	26.30000
LogP	7.64
Vapour Pressure	0.0±0.8 mmHg at 25°C
Index of Refraction	1.465
Storage condition	2-8°C

Symbol	GHS02, GHS07, GHS08, GHS09
Signal Word	Danger
Hazard Statements	H225-H304-H315-H336-H410
Precautionary Statements	P210-P261-P273-P301 + P310-P331-P501
Personal Protective Equipment	Eyeshields;Gloves
Hazard Codes	F,Xn,N
Risk Phrases	R11
Safety Phrases	23-24/25-62-61-60-33-29-16-9
RIDADR	UN 1206 3/PG 2
WGK Germany	1
HS Code	2916190090

Precursor 9
67-56-1 544-35-4 60-33-3 1360168-38-2
124-41-4 64833-94-9 62439-44-5 1190-63-2
17673-53-9
DownStream 10
33001-45-5 127592-95-4 18418-21-8 544-35-4
506-43-4 14606-78-1 553-90-2 627-93-0
1732-10-1 1119-40-0

HS Code	2916190090
Summary	2916190090 unsaturated acyclic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:6.5%。general tariff:30.0%

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