Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Palmitic acid
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Purity: 98.0%
Stocking Period: 10 Day
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: S-Carboxymethyl-L-cysteine
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Purity: 98.0%
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Henan Tianfu Chemical Co., Ltd.
China
Product Name: Carbocistein
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Purity: 99.0%
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Zhongshan Xingrui Chemical Co. , Ltd.
China
Product Name: Carbocisteine
Price: ￥Inquiry/25kg
Purity: 99.0%
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Contact: Wang Jie
Email: 3096638339@qq.com

638-23-3

638-23-3 structure

638-23-3 structure

Name: Carbocisteine
Chemical Name: S-carboxymethyl-L-cysteine
CAS Number: 638-23-3
Molecular Formula: C₅H₉NO₄S
Molecular Weight: 179.194
Catalog: Biochemical Amino acids and their derivatives Other protected amino acids
Create Date: 2018-03-17 08:00:00
Modify Date: 2026-07-03 18:16:41
Carbocisteine, a mucolytic agent, can be used for the research of chronic obstructive pulmonary disease (COPD)[1].

Name	S-carboxymethyl-L-cysteine
Synonyms	(R)-2-AMINO-3-(CBOXYMETHYLTHIO)PROPIONIC ACID s-cboxylmethyl-l-cysteine CBOXYMETHYLCYSTEINE EINECS 211-327-5 3-[(CBOXYMETHYL)THIO]ALANINE Cbocisteine S-CMS Thiodril Mucolase (R)-2-amino-3-((cboxyMethyl)thio)propanoic acid Pulmoclase rhinathiol H-CYS(CBOXYMETHYL)-OH Mucicl Cbocit Fluifort Mucocis L-Serine, O-acetyl-,hydrochloride (1:1) S -（Cboxymethyl）-L-cysteine [L-Cbocisteine] CBOCISTEINE API S-Carboxymethylcysteine 3-[(Carboxymethyl)thio]-L-alanine L-Cysteine, S-(cboxymethyl)- (9CI) carbocisteine Mucopront S-CboxyMethyl-L-cysteine, R DF 1794Y 3-CBOXYMETHYLTHIO-L-ALANINE (2R)-2-Amino-3-[(cboxyMethyl)thio]propionic Acid Siroxyl Reomucil L-CYSTEINE, S-(CBOXYMETHYL) Rhinathiol Lisomucil S-Cboxymethyl-L-cy s-(cboxymethyl)-(r)-cysteine s-(cboxymethyl)-l-cystein CBOCYSTEINE Carbocysteine S-Cboxymethyl-L-cysteine thiodril MFCD00002614 Loviscol rinatiol Cbocysteine 3-[(Cboxymethyl)thio]alanine 3-(Carboxymethylthio)-L-alanine Rhinatiol L-Carbocisteine (l)-2-amino-3-(cboxymethylthio)propionicacid S- Cbomethylcysteine Muciclar Mucofan (r)-s-(cboxymethyl)cysteine Mucolex carbocisteine API l-cboxymethylcysteine Mukinyl l.j H-L-CYS(ACOH)-OH Carbocistein Pectox Mucodyne Mucotab Transbronchin CBOXYMETHYL-L-CYSTEINE Bronchokod l-3-((cboxymethyl)thio)alanine S-(Carboxymethyl)-L-cysteine S-CboxyMethyl-L-Cysteine Sulfoxide Lisil S-Carboxymethyl-L-cysteine (2R)-2-ammonio-3-(cboxylatomethylthio)propanoate

Description	Carbocisteine, a mucolytic agent, can be used for the research of chronic obstructive pulmonary disease (COPD)[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. Paola Rogliani, et al. Efficacy and safety profile of mucolytic/antioxidant agents in chronic obstructive pulmonary disease: a comparative analysis across erdosteine, carbocysteine, and N-acetylcysteine. Respir Res. 2019 May 27;20(1):104.

Density	1.5±0.1 g/cm3
Boiling Point	417.3±45.0 °C at 760 mmHg
Melting Point	208-213 °C (dec.)
Molecular Formula	C₅H₉NO₄S
Molecular Weight	179.194
Flash Point	206.2±28.7 °C
Exact Mass	179.025223
PSA	125.92000
LogP	0.32
Vapour Pressure	0.0±2.1 mmHg at 25°C
Index of Refraction	1.588
Water Solubility	SOLUBLE IN COLD WATER

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AY4342000

CHEMICAL NAME :: Alanine, 3-((carboxymethyl)thio)-, L-

CAS REGISTRY NUMBER :: 638-23-3

BEILSTEIN REFERENCE NO. :: 1725012

LAST UPDATED :: 199707

DATA ITEMS CITED :: 9

MOLECULAR FORMULA :: C5-H9-N-O4-S

MOLECULAR WEIGHT :: 179.21

WISWESSER LINE NOTATION :: QVYZ1S1VQ -L

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >15 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959- Volume(issue)/page/year: 24,1705,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 7800 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,190,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 10300 mg/kg

TOXIC EFFECTS :: Behavioral - ataxia

REFERENCE :: YKYUA6 Yakkyoku. Pharmacy. (Nanzando, 4-1-11, Yushima, Bunkyo-ku, Tokyo, Japan) V.1- 1950- Volume(issue)/page/year: 32,993,1981

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 8400 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,190,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1433 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 94,1419,1974

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 9 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,190,1982 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 11250 mg/kg/30D-I

TOXIC EFFECTS :: Blood - changes in erythrocyte (RBC) count Blood - changes in platelet count Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases

REFERENCE :: YKYUA6 Yakkyoku. Pharmacy. (Nanzando, 4-1-11, Yushima, Bunkyo-ku, Tokyo, Japan) V.1- 1950- Volume(issue)/page/year: 32,993,1981 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 625 mg/kg

SEX/DURATION :: female 17-21 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Newborn - physical

REFERENCE :: KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 13,1311,1979

Hazard Codes	Xi
Risk Phrases	36/37/38
Safety Phrases	S24/25
RIDADR	NONH for all modes of transport
WGK Germany	2
RTECS	AY4342000
HS Code	2930909090

Precursor 10
52-90-4 3926-62-3 64-69-7 56-89-3
10318-18-0 2731-73-9 68-11-1 79-11-8
5147-00-2 2150-55-2
DownStream 3
5472-74-2 6332-29-2 5439-87-2

HS Code	2930909090
Summary	2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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