Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Carbocisteine
Price:
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Carbocisteine
Price: ￥108.0/1g ￥178.0/5g
Purity: 98.0%
Stocking Period: 1 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Carbocysteine
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: S-Carboxymethyl-L-cysteine
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Henan Tianfu Chemical Co., Ltd.
China
Product Name: Carbocistein
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

638-23-3

638-23-3 structure

638-23-3 structure

Name: Carbocisteine
Chemical Name: S-carboxymethyl-L-cysteine
CAS Number: 638-23-3
Molecular Formula: C₅H₉NO₄S
Molecular Weight: 179.194
Catalog: Biochemical Amino acids and their derivatives Other protected amino acids
Create Date: 2018-03-17 08:00:00
Modify Date: 2024-01-02 12:12:36
Carbocisteine, a mucolytic agent, can be used for the research of chronic obstructive pulmonary disease (COPD)[1].

Name	S-carboxymethyl-L-cysteine
Synonyms	EINECS 211-327-5 Carbocysteine MFCD00002614 Loviscol Thiodril Alanine, 3-((carboxymethyl)thio)-, L- 3-(Carboxymethylthio)-L-alanine L-Carbocisteine Muciclar Fluifort Mucocis L-Cysteine, S- (carboxymethyl)- S-Carboxymethylcysteine 3-[(Carboxymethyl)thio]-L-alanine L-Cysteine, S-(carboxymethyl)- carbocisteine Carbocistein Mucodyne Transbronchin Reomucil S-(Carboxymethyl)-L-cysteine Rhinathiol S-Carboxymethyl-L-cysteine Lisomucil carbocisteine API

Description	Carbocisteine, a mucolytic agent, can be used for the research of chronic obstructive pulmonary disease (COPD)[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. Paola Rogliani, et al. Efficacy and safety profile of mucolytic/antioxidant agents in chronic obstructive pulmonary disease: a comparative analysis across erdosteine, carbocysteine, and N-acetylcysteine. Respir Res. 2019 May 27;20(1):104.

Density	1.5±0.1 g/cm3
Boiling Point	417.3±45.0 °C at 760 mmHg
Melting Point	208-213 °C (dec.)
Molecular Formula	C₅H₉NO₄S
Molecular Weight	179.194
Flash Point	206.2±28.7 °C
Exact Mass	179.025223
PSA	125.92000
LogP	0.32
Vapour Pressure	0.0±2.1 mmHg at 25°C
Index of Refraction	1.588
Water Solubility	SOLUBLE IN COLD WATER

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AY4342000

CHEMICAL NAME :: Alanine, 3-((carboxymethyl)thio)-, L-

CAS REGISTRY NUMBER :: 638-23-3

BEILSTEIN REFERENCE NO. :: 1725012

LAST UPDATED :: 199707

DATA ITEMS CITED :: 9

MOLECULAR FORMULA :: C5-H9-N-O4-S

MOLECULAR WEIGHT :: 179.21

WISWESSER LINE NOTATION :: QVYZ1S1VQ -L

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >15 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959- Volume(issue)/page/year: 24,1705,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 7800 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,190,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 10300 mg/kg

TOXIC EFFECTS :: Behavioral - ataxia

REFERENCE :: YKYUA6 Yakkyoku. Pharmacy. (Nanzando, 4-1-11, Yushima, Bunkyo-ku, Tokyo, Japan) V.1- 1950- Volume(issue)/page/year: 32,993,1981

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 8400 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,190,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1433 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 94,1419,1974

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 9 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,190,1982 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 11250 mg/kg/30D-I

TOXIC EFFECTS :: Blood - changes in erythrocyte (RBC) count Blood - changes in platelet count Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases

REFERENCE :: YKYUA6 Yakkyoku. Pharmacy. (Nanzando, 4-1-11, Yushima, Bunkyo-ku, Tokyo, Japan) V.1- 1950- Volume(issue)/page/year: 32,993,1981 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 625 mg/kg

SEX/DURATION :: female 17-21 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Newborn - physical

REFERENCE :: KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 13,1311,1979

Hazard Codes	Xi
Risk Phrases	36/37/38
Safety Phrases	S24/25
RIDADR	NONH for all modes of transport
WGK Germany	2
RTECS	AY4342000
HS Code	2930909090

Precursor 10
52-90-4 3926-62-3 64-69-7 56-89-3
10318-18-0 2731-73-9 68-11-1 79-11-8
5147-00-2 2150-55-2
DownStream 3
5472-74-2 6332-29-2 5439-87-2

HS Code	2930909090
Summary	2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%