Tubulin polymerization-IN-38
Modify Date: 2024-01-12 11:45:32
Tubulin polymerization-IN-38 structure
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Common Name | Tubulin polymerization-IN-38 | ||
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| CAS Number | 1005192-31-3 | Molecular Weight | 638.82 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C31H50N4O8S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Tubulin polymerization-IN-38Tubulin polymerization-IN-38 a Tubulysin (HY-128914) analogue, is a potent anticancer agent. Tubulin polymerization-IN-38 inhibits tubulin polymerisation and thereby inducing apoptosis. Tubulin polymerization-IN-38 has cytotoxicity against cancer cells[1]. |
| Name | Tubulin polymerization-IN-38 |
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| Description | Tubulin polymerization-IN-38 a Tubulysin (HY-128914) analogue, is a potent anticancer agent. Tubulin polymerization-IN-38 inhibits tubulin polymerisation and thereby inducing apoptosis. Tubulin polymerization-IN-38 has cytotoxicity against cancer cells[1]. |
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| Related Catalog | |
| Target |
Tubulin polymerisation[1] |
| In Vitro | Tubulin polymerization-IN-38 (example 5) exhibits cytotoxicity against L929, SW-480 and KB-3-1 with IC50s of 2.2 ng/mL, 0.35 ng/mL and 1.5 ng/mL, respectively[1]. |
| References |
[1]. Jonathan A. Ellman, et al. Tubulysin d analogues. WO2009012958A2. |
| Molecular Formula | C31H50N4O8S |
|---|---|
| Molecular Weight | 638.82 |