Tubulin polymerization-IN-16

Modify Date: 2025-08-27 11:20:09

Tubulin polymerization-IN-16 structure	Common Name	Tubulin polymerization-IN-16
	CAS Number	2296731-38-7	Molecular Weight	465.50
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₄H₂₇N₅O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Tubulin polymerization-IN-16

Tubulin polymerization-IN-16 (compound 5g) is a potent inhibitor of tubulin polymerization. Tubulin polymerization-IN-16 shows most potent against cancer cells, with IC50 values of 0.084-0.221 μM. Tubulin polymerization-IN-16 potently disrupts microtubule/tubulin dynamics, induces cell cycle arrest at G2/M phase in SGC-7901 cells[1].

Name	Tubulin polymerization-IN-16

Description	Tubulin polymerization-IN-16 (compound 5g) is a potent inhibitor of tubulin polymerization. Tubulin polymerization-IN-16 shows most potent against cancer cells, with IC50 values of 0.084-0.221 μM. Tubulin polymerization-IN-16 potently disrupts microtubule/tubulin dynamics, induces cell cycle arrest at G2/M phase in SGC-7901 cells[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Microtubule/Tubulin Signaling Pathways >> Cytoskeleton >> Microtubule/Tubulin
References	[1]. Huang L, et al. Design, synthesis and bio-evaluation of novel 2-aryl-4-(3,4,5-trimethoxy-benzoyl)-5-substituted-1,2,3-triazoles as the tubulin polymerization inhibitors. Eur J Med Chem. 2020;186:111846.

Molecular Formula	C₂₄H₂₇N₅O₅
Molecular Weight	465.50

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Tubulin polymerization-IN-16

Use of Tubulin polymerization-IN-16

Names

Tubulin polymerization-IN-16 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.