p38 MAPK-IN-1

Modify Date: 2024-01-11 01:35:03

p38 MAPK-IN-1 Structure
p38 MAPK-IN-1 structure
Common Name p38 MAPK-IN-1
CAS Number 1006378-90-0 Molecular Weight 349.35
Density 1.3±0.1 g/cm3 Boiling Point 527.0±50.0 °C at 760 mmHg
Molecular Formula C21H15F2N2O Melting Point N/A
MSDS N/A Flash Point 272.5±30.1 °C

 Use of p38 MAPK-IN-1


p38 MAPK-IN-1 is a novel potent and selective inhibitor of p38 MAPK with IC50 of 68 nM, shows sustained levels, low clearance and good bioavailability.

 Names

Name p38 MAPK-IN-1
Synonym More Synonyms

 p38 MAPK-IN-1 Biological Activity

Description p38 MAPK-IN-1 is a novel potent and selective inhibitor of p38 MAPK with IC50 of 68 nM, shows sustained levels, low clearance and good bioavailability.
Related Catalog
References

[1]. Lumeras W, et al. 1,7-Naphthyridine 1-oxides as novel potent and selective inhibitors of p38 mitogen activated protein kinase. J Med Chem. 2011 Nov 24;54(22):7899-910.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 527.0±50.0 °C at 760 mmHg
Molecular Formula C21H15F2N2O
Molecular Weight 349.35
Flash Point 272.5±30.1 °C
LogP 2.46
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.622
Storage condition 2-8℃

 Synonyms

1,7-Naphthyridine, 4-(2,4-difluorophenyl)-8-(2-methylphenyl)-, 7-oxide
4-(2,4-Difluorophenyl)-8-(2-methylphenyl)-1,7-naphthyridine 7-oxide
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Price: $462/10mM*1mLinDMSO

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