Tenovin-3

Modify Date: 2024-01-04 11:52:39

Tenovin-3 Structure
Tenovin-3 structure
Common Name Tenovin-3
CAS Number 1011301-27-1 Molecular Weight 327.444
Density 1.2±0.1 g/cm3 Boiling Point N/A
Molecular Formula C18H21N3OS Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Tenovin-3


Tenovin-3 is able to increase p53 levels, determined in MCF-7 cells treated for 6 hr at 10 μM.Target: p53in vitro: Tenovins inhibit the activities of human SirT1 and SirT2, two members of the NAD+-dependent class III histone deacetylases that also belong to the sirtuin family.[1]

 Names

Name N-[(4-aminophenyl)carbamothioyl]-4-tert-butylbenzamide
Synonym More Synonyms

 Tenovin-3 Biological Activity

Description Tenovin-3 is able to increase p53 levels, determined in MCF-7 cells treated for 6 hr at 10 μM.Target: p53in vitro: Tenovins inhibit the activities of human SirT1 and SirT2, two members of the NAD+-dependent class III histone deacetylases that also belong to the sirtuin family.[1]
Related Catalog
References

[1]. Lain S, et al. Discovery, in vivo activity, and mechanism of action of a small-molecule p53 activator. Cancer Cell. 2008 May;13(5):454-63.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Molecular Formula C18H21N3OS
Molecular Weight 327.444
Exact Mass 327.140533
PSA 109.77000
LogP 2.82
Appearance of Characters yellow solid
Index of Refraction 1.662
Storage condition -20℃

 Synonyms

N-[(4-Aminophenyl)carbamothioyl]-4-(2-methyl-2-propanyl)benzamide
QC-514
1-(4-amino-phenyl)-3-(4-tert-butyl-benzoyl)-thiourea
N-[(4-aminophenyl)-carbamothioyl]-4-tert-butyl-benzamide
Benzamide, N-[[(4-aminophenyl)amino]thioxomethyl]-4-(1,1-dimethylethyl)-
Tenovin-3
Top Suppliers:I want be here




Get all suppliers and price by the below link:

Tenovin-3 suppliers


Price: $130/10mM*1mLinDMSO

Reference only. check more Tenovin-3 price