Minoxidil-d10
Modify Date: 2024-01-30 21:52:31
Minoxidil-d10 structure
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Common Name | Minoxidil-d10 | ||
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| CAS Number | 1020718-66-4 | Molecular Weight | 219.310 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 544.9±60.0 °C at 760 mmHg | |
| Molecular Formula | C9H5D10N5O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 283.4±32.9 °C | |
Use of Minoxidil-d10Minoxidil-d10 (U10858-d10) is the deuterium labeled Minoxidil. Minoxidil (U10858) is an ATP-sensitive potassium (KATP) channel opener, a potent oral antihypertensive agent and a peripheral vasodilator that promotes vasodilation also affects hair growth. Minoxidil is also a potent inhibitor of soybean lipoxygenaseare with an IC50 of 20 μM[1][2][3]. |
| Name | 6-[(2H10)-1-Piperidinyl]-2,4-pyrimidinediamine 3-oxide |
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| Synonym | More Synonyms |
| Description | Minoxidil-d10 (U10858-d10) is the deuterium labeled Minoxidil. Minoxidil (U10858) is an ATP-sensitive potassium (KATP) channel opener, a potent oral antihypertensive agent and a peripheral vasodilator that promotes vasodilation also affects hair growth. Minoxidil is also a potent inhibitor of soybean lipoxygenaseare with an IC50 of 20 μM[1][2][3]. |
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| Related Catalog | |
| In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 544.9±60.0 °C at 760 mmHg |
| Molecular Formula | C9H5D10N5O |
| Molecular Weight | 219.310 |
| Flash Point | 283.4±32.9 °C |
| Exact Mass | 219.190430 |
| LogP | -0.41 |
| Vapour Pressure | 0.0±1.5 mmHg at 25°C |
| Index of Refraction | 1.724 |
| 2,4-pyrimidinediamine, 6-(1-piperidinyl-d10)-, 3-oxide |
| 6-[(2H10)-1-Piperidinyl]-2,4-pyrimidinediamine 3-oxide |
| 6-[(2H10)Piperidin-1-yl]pyrimidine-2,4-diamine 3-oxide |