4-Methoxyphenylacetic acid

Modify Date: 2025-08-21 09:10:58

4-Methoxyphenylacetic acid structure	Common Name	4-Methoxyphenylacetic acid
	CAS Number	104-01-8	Molecular Weight	166.174
	Density	1.2±0.1 g/cm3	Boiling Point	306.0±17.0 °C at 760 mmHg
	Molecular Formula	C₉H₁₀O₃	Melting Point	84-86 °C(lit.)
	MSDS	Chinese USA	Flash Point	124.3±14.4 °C
	Symbol	GHS05, GHS07	Signal Word	Danger

Use of 4-Methoxyphenylacetic acid

2-(4-Methoxyphenyl)acetic acid is a plasma metabolite, with high sensitivity and specificity value as a biomarker for discriminating between NSCLC and healthy controls.

Name	4-methoxyphenylacetic acid
Synonym	More Synonyms

Description	2-(4-Methoxyphenyl)acetic acid is a plasma metabolite, with high sensitivity and specificity value as a biomarker for discriminating between NSCLC and healthy controls.
Related Catalog	Natural Products >> Acids and Aldehydes Research Areas >> Cancer
Target	Human Endogenous Metabolite
In Vitro	2-(4-Methoxyphenyl)acetic acid (4-methoxyphenylacetic acid) is a plasma metabolite, with high sensitivity and specificity values as a biomarker for discriminating between NSCLC and healthy controls. 2-(4-Methoxyphenyl)acetic acid may play a protective role to prevent the development of lung cancer[1].
References	[1]. Xiang C, et al. Cortisol, cortisone, and 4-methoxyphenylacetic acid as potential plasma biomarkers for early detection of non-small cell lung cancer. Int J Biol Markers. 2018 Aug;33(3):314-320.

Density	1.2±0.1 g/cm3
Boiling Point	306.0±17.0 °C at 760 mmHg
Melting Point	84-86 °C(lit.)
Molecular Formula	C₉H₁₀O₃
Molecular Weight	166.174
Flash Point	124.3±14.4 °C
Exact Mass	166.062988
PSA	46.53000
LogP	1.42
Vapour Pressure	0.0±0.7 mmHg at 25°C
Index of Refraction	1.538
InChIKey	NRPFNQUDKRYCNX-UHFFFAOYSA-N
SMILES	COc1ccc(CC(=O)O)cc1
Water Solubility	6 g/L (20 ºC)

4-Methoxyphenylacetic acid MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AI8960000

CHEMICAL NAME :: Acetic acid, p-methoxyphenyl-

CAS REGISTRY NUMBER :: 104-01-8

BEILSTEIN REFERENCE NO. :: 1101737

LAST UPDATED :: 199710

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C9-H10-O3

MOLECULAR WEIGHT :: 166.19

WISWESSER LINE NOTATION :: QV1R DO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0530656-1 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1550 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 14,685,1976

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 504 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 20,709,1977 ** TUMORIGENIC DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 63 gm/kg/78W-I

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Lungs, Thorax, or Respiration - tumors

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB223-159 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83216 No. of Facilities: 21 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 373 (estimated)

Symbol	GHS05, GHS07
Signal Word	Danger
Hazard Statements	H302-H315-H318-H335
Precautionary Statements	P261-P280-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn:Harmful
Risk Phrases	R22;R36/37/38
Safety Phrases	S26-S36
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	AI8960000
HS Code	29189090

Precursor 9
CAS#:14062-18-1 Ethyl (4-methox... CAS#:23786-14-3 Methyl (4-metho... CAS#:702-23-8 2-(4-Methoxyphe... CAS#:6832-17-3 2-diazonio-1-(4...
CAS#:124-38-9 Carbon dioxide CAS#:824-94-2 4-Methoxybenzyl... CAS#:14337-31-6 BENZENEMETHANOL... CAS#:60512-57-4 1-(2,2-dibromoe...
CAS#:104-47-2 (4-Methoxypheny...
DownStream 10
CAS#:10499-17-9 3-(4-methoxyphe... CAS#:110005-81-7 2-hydroxy-5-(2-... CAS#:4091-50-3 phenethylamine,... CAS#:3722-56-3 (3S)-3,4-Dihydr...
CAS#:491-80-5 biochanin A CAS#:34837-88-2 4-METHOXY-3-NIT... CAS#:57676-49-0 (4-Methoxypheny... CAS#:123-11-5 4-Methoxybenzal...
CAS#:100-09-4 p-Anisic acid CAS#:143589-97-3 (S)-4-Benzyl-3-...

HS Code	2918990090
Summary	2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

A metabolite profiling approach to identify biomarkers of flavonoid intake in humans.

J. Nucl. Med. 139 , 2309-14, (2009)

Flavonoids are phytochemicals that are widespread in the human diet. Despite limitations in their bioavailability, experimental and epidemiological data suggest health benefits of flavonoid consumptio...

Mass spectrometric behavior of phenolic acids standards and their analysis in the plant samples with LC/ESI/MS system.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 967 , 21-7, (2014)

Liquid chromatography coupled to mass spectrometry (MS) with electrospray ionization (ESI) is one of analytical techniques to obtain accurate results of low molecular weight aromatic compounds in biol...

High-performance liquid chromatographic method for screening disorders of aromatic acid metabolism using a multi-detection system.

J. Chromatogr. A. 310(2) , 273-81, (1984)

This paper describes the use of a high-performance liquid chromatograph equipped with an ultraviolet multi-detection system for the analysis of aromatic acids to help establish a high-risk screening s...

2-(4-methoxyphenyl)acetic acid

Benzeneacetic acid, 4-methoxy-

4-Methoxyphenylacetic acid

EINECS 203-166-4

(4-Methoxyphenyl)acetic acid

QV1R DO1

Homoanisic Acid

MFCD00004345

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 4-Methoxyphenylacetic acid
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: 4-Methoxyphenylacetic acid
Price: ￥508.0/500g ￥138.0/100g
Purity: 99.0%
Delivery: 1 Day
Contact: Liu jia
Email: 2130147988@qq.com

DC Chemicals Limited
China
Product Name: 4-Methoxyphenylacetic acid
Price: $280.0/20mg
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 4-Methoxyphenylacetic acid
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: TIANFU CHEM---4-Methoxyphenylacetic acid
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Anson
Email: info@tianfuchem.com

Zhongshan Xingrui Chemical Co. , Ltd.
China
Product Name: 4-Methoxyphenylacetic acid
Price: ￥Inquiry/25kg
Purity: 99.0%
Delivery: Inquiry
Contact: Wang Jie
Email: 3096638339@qq.com

Get all suppliers and price by the below link:

4-Methoxyphenylacetic acid suppliers

Price: ￥550/10 mM * 1 mL in DMSO

Reference only. check more 4-Methoxyphenylacetic acid price

4-Methoxyphenylacetic acid

Use of 4-Methoxyphenylacetic acid

Names