Atipamezole hydrochloride

Modify Date: 2024-01-02 11:01:06

Atipamezole hydrochloride structure	Common Name	Atipamezole hydrochloride
	CAS Number	104075-48-1	Molecular Weight	248.751
	Density	1.115g/cm3	Boiling Point	367.1ºC at 760mmHg
	Molecular Formula	C₁₄H₁₇ClN₂	Melting Point	N/A
	MSDS	N/A	Flash Point	178ºC

Use of Atipamezole hydrochloride

Atipamezole hydrochloride is a synthetic α2-adrenoceptor antagonist with a Ki of 1.6 nM.

Name	Atipamezole hydrochloride
Synonym	More Synonyms

Description	Atipamezole hydrochloride is a synthetic α2-adrenoceptor antagonist with a Ki of 1.6 nM.
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor Research Areas >> Neurological Disease
Target	Ki: 1.6 nM[1]
In Vitro	The affinity of atipamezole for α2-adrenoceptors and its α2/α1 selectivity ratio are considerably higher than yohimbine. Atipamezole is not selective for subtypes of α2-adrenoceptors. It has negligible affinity for 5-HT1, 5-HT2 and I2 bindings sites[1].
In Vivo	Atipamezole is well tolerated in rodents. In anesthetized, normotensive rats, the cardiovascular effects of atipamezole (0.01–1 mg/kg, i.v.) are rather modest. Atipamezole is commonly used by veterinarians to awaken animals from sedation or anesthesia. Atipamezole increases sexual activity in rats and monkeys. In animals with sustained nociception, atipamezole increases pain-related responses by blocking the noradrenergic feedback inhibition of pain. Atipamezole at low doses has beneficial effects on alertness, selective attention, planning, learning, and recall in experimental animals, but not necessarily on short-term working memory[1].
References	[1]. Pertovaara A, et al.Pharmacological properties, central nervous system effects, and potential therapeutic applicationsof atipamezole, a selective alpha2-adrenoceptor antagonist. CNS Drug Rev. 2005 Autumn;11(3):273-88.

HS Code	2933290090

HS Code	2933290090
Summary	2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

5-(2-Ethyl-2,3-dihydro-1H-indene-2-yl)-1H-imidazole hydrochloride

1H-Imidazole, 5-(2-ethyl-2,3-dihydro-1H-inden-2-yl)-, hydrochloride (1:1)

Atipamezole hydrochloride

4-(2-Ethyl-2,3-dihydro-1H-inden-2-yl)-1H-imidazole hydrochloride (1:1)

1H-Imidazole,4-(2-ethyl-2,3-dihydro-1H-inden-2-yl)-,monohydrochloride

4-(2-Ethyl-2,3-dihydro-1H-inden-2-yl)-1H-imidazole hydrochloride

4-(2-Ethyl-2-indanyl)imidazole hydrochloride

Atipamezole HCL

5-(2-Ethyl-2,3-dihydro-1H-indene-2-yl)-1H-imidazolehydrochloride

Atipamezole (hydrochloride)

Get all suppliers and price by the below link:

Price: $106/10mM*1mLinDMSO