Collagen-IN-1

Modify Date: 2024-01-02 16:49:48

Collagen-IN-1 Structure
Collagen-IN-1 structure
Common Name Collagen-IN-1
CAS Number 104260-73-3 Molecular Weight 230.26
Density N/A Boiling Point N/A
Molecular Formula C14H14O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Collagen-IN-1


Collagen-IN-1 (compound 3), an ortho-carbonyl hydroquinone derivative, is a selective inhibitor on collagen. Collagen-IN-1 inhibits agonist-induced platelet aggregation in a non-competitive manner with an IC50 value of 1.77 μM. Collagen-IN-1 reduces the expression of P-selectin, activation of glycoprotein IIb/IIIa, and release of adenosine triphosphate and CD63 from platelet. Collagen-IN-1 has the potential for platelet-related thrombosis diseases research[1].

 Names

Name Collagen-IN-1

 Collagen-IN-1 Biological Activity

Description Collagen-IN-1 (compound 3), an ortho-carbonyl hydroquinone derivative, is a selective inhibitor on collagen. Collagen-IN-1 inhibits agonist-induced platelet aggregation in a non-competitive manner with an IC50 value of 1.77 μM. Collagen-IN-1 reduces the expression of P-selectin, activation of glycoprotein IIb/IIIa, and release of adenosine triphosphate and CD63 from platelet. Collagen-IN-1 has the potential for platelet-related thrombosis diseases research[1].
Related Catalog
References

[1]. Diego Méndez, et al. Synthesis of antiplatelet ortho-carbonyl hydroquinones with differential action on platelet aggregation stimulated by collagen or TRAP-6. Eur J Med Chem. 2020 Apr 15;192:112187.

 Chemical & Physical Properties

Molecular Formula C14H14O3
Molecular Weight 230.26
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.